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January 2024 in “Proceedings of the National Academy of Sciences of the United States of America” The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.
49 citations
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July 2000 in “Journal of Histochemistry & Cytochemistry” POMC-derived peptides are important for skin functions like immune response and stress management.
April 2026 in “Experimental & Molecular Medicine” Mouse and human skin development share similar fibroblast timelines.
178 citations
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April 2011 in “Journal of Clinical Investigation” Basal cell carcinomas in mice can start from hair follicle stem cells and other skin cell types, depending on signaling levels.
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January 2008 in “Indian Journal of Dermatology” Pigmentary mosaicism causes skin color changes and can affect multiple body systems, but has no cure.
5 citations
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January 2016 in “Stem Cells International” Certain skin cells near the base of hair muscles may help renew and stabilize skin, possibly affecting skin disorder understanding.
May 2004 in “International Journal of Cosmetic Science” Melanogenesis inhibitors like kojic acid and niacinamide can reduce inflammation and pigment production in skin cells.
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February 2023 in “Cosmetics” Nostoc verrucosum extracts may help reduce melanin production and have antioxidant properties.
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May 2018 in “Cancer Cell” Less differentiated melanoma cells are more vulnerable to a type of cell death, which could improve cancer treatments.
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March 2019 in “Journal of Biomedical Materials Research Part A” Sulfated hyaluronan in collagen helps hair follicle cells grow and develop better for skin grafts.
352 citations
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August 2003 in “Proceedings of the National Academy of Sciences” Nestin is found in hair follicle progenitor cells, linking them to neural stem cells.
August 2020 in “Research Square (Research Square)” Oxygen levels affect hair growth and color cells differently when they interact directly.
153 citations
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April 1998 in “Current Biology” The risk of skin tumors becoming malignant depends on the specific skin cell type affected.
23 citations
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June 2015 in “Oncology Letters” Adipose-derived stem cell-conditioned medium can reduce melanoma cell growth and spread.
26 citations
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July 2007 in “Biochemical Pharmacology” ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
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February 2018 in “Archives of Pharmacal Research” Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.
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May 2006 in “The FASEB journal” Oxidative stress causes hair to gray by damaging and killing pigment cells.
467 citations
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May 1999 in “Molecular Cell” Activating c-Myc in skin causes rapid cell growth and changes, but these effects are reversible.
April 2016 in “Journal of Investigative Dermatology” Tumor cell adhesion is linked to higher risk of SLN metastasis and melanoma recurrence, and a model including these factors predicts these outcomes better than one with just clinical data.
56 citations
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February 2012 in “Cell Cycle” MicroRNAs are crucial for controlling skin development and healing by regulating genes.
June 2004 in “Journal of Investigative Dermatology” Increased pigmentation may protect skin from UVB, new targets for skin disease treatments were identified, sunscreen ingredients don't affect hormones, TNF-α inhibitors may help diabetic wounds, and certain treatments could prevent chemotherapy-induced hair loss.
April 2012 in “Development” Rac1 is crucial for normal hair structure and pigmentation.
6 citations
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March 2009 in “Pigment Cell & Melanoma Research” A sphingolipid from human placenta may help treat vitiligo by activating melanocyte stem cells.
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January 2024 in “Science Advances” Touch dome keratinocytes in adult skin have traits of different skin cell types.
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July 2013 in “Acta Biochimica Polonica” Chemotherapy reduces splenic melanin in mice.
28 citations
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July 2005 in “Journal of Investigative Dermatology” Sca-1+ cells in newborn mouse skin may become fat cells.
8 citations
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July 2016 in “Oncotarget” Lgr5+ stem cells do not cause skin tumors.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” The model can effectively test gene functions and drug responses in human skin.
November 2022 in “Journal of Investigative Dermatology” Scientists found a new type of skin cell that could help with skin repair and these cells work better with a certain protein.