77 citations
,
February 2017 in “Stem Cell Reports” SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.
40 citations
,
June 2011 in “Journal of biological chemistry/The Journal of biological chemistry” FA2H is essential for normal fur and sebum production in mice.
29 citations
,
March 2011 in “The Journal of Nutritional Biochemistry” Eating isoflavone can help mice grow hair by increasing a growth factor.
March 2024 in “GSC Advanced Research and Reviews” Different light affects cell functions and can help treat skin conditions.
January 2021 in “Journal of clinical and cosmetic dermatology” Human skin responds to light with protective mechanisms, but more research is needed to understand these processes and their implications for health and therapy.
13 citations
,
January 2009 in “The Open Dermatology Journal” Oral pigmentation can be a sign of Addison's disease.
2 citations
,
April 2023 in “South East European Journal of Immunology” High leptin levels may promote skin cancer and inflammation, suggesting potential for leptin-targeted therapies.
70 citations
,
February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
May 2021 in “GSC Advanced Research and Reviews” Hair color is influenced by genetics and can indicate certain health conditions.
32 citations
,
April 2016 in “Journal of Investigative Dermatology” STAT5 activation is crucial for starting the hair growth phase.
30 citations
,
December 2018 in “Trends in Endocrinology and Metabolism” Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.
June 2023 in “Animal Bioscience” Vimentin and transthyretin proteins are linked to black coat color in sheep.
75 citations
,
January 2009 in “International journal of trichology” Hair grays due to oxidative stress and fewer functioning melanocytes.
67 citations
,
January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
20 citations
,
January 2015 in “Current problems in dermatology” Graying hair happens due to aging and might be delayed by new treatments.
16 citations
,
July 2012 in “Current pharmaceutical biotechnology” New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
2 citations
,
January 2023 in “International journal of biological sciences” Gray hair can potentially be reversed, leading to new treatments.
81 citations
,
February 2019 in “Experimental & Molecular Medicine” PAK4 is crucial in cancer progression, brain development, and could be a therapeutic target, especially through the PAK4-CREB axis.
65 citations
,
September 2017 in “British Journal of Cancer” Black ethnicity, prior PSA tests, enlarged prostate, and family history increase prostate cancer risk; Asian ethnicity, obesity, smoking, diabetes, and less sexual activity or no children decrease risk.
42 citations
,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
26 citations
,
June 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Regenerative therapies show promise for treating vitiligo and alopecia areata.
3 citations
,
January 2019 in “Advances in stem cells and their niches” Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.
1 citations
,
April 2023 in “African Scientific Reports” Natural compounds can lighten skin by reducing melanin.
1 citations
,
January 2012 in “Elsevier eBooks” The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.
1 citations
,
January 2009 in “Elsevier eBooks” The document concludes that a deeper understanding of skin aging and photodamage is needed to create better skin treatments.
May 2026 in “Commagene Journal of Biology” Anti-aging peptides can improve skin appearance but need better delivery methods and more research.
April 2026 in “npj Regenerative Medicine” Melanocyte stem cells in hair follicles are key to understanding and potentially preventing hair graying.
March 2026 in “International Journal of Dermatology Venereology and Leprosy Sciences” Vitiligo treatment requires a personalized mix of therapies to restore skin color and improve life quality.
January 2026 in “Animal Advances” Genes linked to coat color and fiber length in Chinese goats were identified.
November 2025 in “EXPERIMENTAL ANIMALS” Stingless bee propolis may help regenerate hair follicles and improve pigment function in chemotherapy-induced hair loss.