research Regulation of somatic cell reprogramming through inducible mir-302 expression
Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.
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research Development of a Chitosan Nanofibrillar Scaffold for Skin Repair and Regeneration
Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.
research Extraskeletal actions of vitamin D
Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.
research Fullerene nanoparticle in dermatological and cosmetic applications
Fullerenes show potential in skin care but need more safety research.
research Characterization of the serotoninergic system in the C57BL/6 mouse skin
Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.
research Role of insulin resistance and diet in acne
Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
research Endogenous human skin equivalent promotes in vitro morphogenesis of follicle-like structures
Endo-HSE helps grow hair-like structures from human skin cells in the lab.
research Thyroid hormone action in epidermal development and homeostasis and its implications in the pathophysiology of the skin
Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.
research Hair follicle stem cells:In vitroandin vivoneural differentiation
Hair follicle stem cells can become different cell types and may help treat neurodegenerative disorders.
research Genome-wide association study of skin complex diseases
Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.
research Differential proteomics of lesional vs. non-lesional biopsies revealed non-immune mechanisms of alopecia areata
Non-immune factors play a significant role in alopecia areata.
research Cell and Tissue Damage after Skin Exposure to Ionizing Radiation: Short- and Long-Term Effects after a Single and Fractional Doses
Ionizing radiation causes irreversible skin damage, with single doses leading to acute injury and hair graying, and fractional doses causing more severe long-term tissue damage.
research RSPO1-mutated keratinocytes from palmoplantar keratoderma display impaired differentiation, alteration of cell–cell adhesion, EMT-like phenotype and invasiveness properties: implications for squamous cell carcinoma susceptibility in patients with 46XX disorder of sexual development
RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.
research Advances in Hair Diseases
The review highlights the importance of stem cells in hair health and suggests new treatment strategies for hair loss conditions.
research The role of janus kinases in the treatment of autoimmune skin diseases
Janus kinase inhibitors show promise in treating autoimmune skin diseases.
research 284 Backhousia citriodora leaf extract: A new active solution to control hyper-seborrhea for multi-ethnic skins
Backhousia citriodora leaf extract effectively reduces oily skin across different ethnic groups.
research MICRO-MORPHOMETRIC STUDY OF SKIN IN DEVELOPING HUMAN FETUSES AND ITS CLINICAL RELEVANCE
Understanding fetal skin development helps diagnose congenital skin diseases.
research Anatomical development of the skin in foetuses of Red Sokoto goats (Capra hircus)
Red Sokoto goat fetuses develop firmer, pigmented skin with hair follicles as they grow.
research Dimorphic regulation of the MafB gene by sex steroids in hamsters (Mesocricetus auratus)
Sex steroids affect the MafB gene differently in male and female hamsters.
research Dynamics and Epigenetics of the Epidermal Differentiation Complex
Epigenetic mechanisms control skin development by regulating gene expression.
research The multiple uses of azelaic acid in dermatology: mechanism of action, preparations, and potential therapeutic applications
Azelaic acid treats acne, rosacea, and hyperpigmentation with minimal side effects.
research Cutaneous Epithelial Stem Cells
Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
research The in vitro plasticity of hair follicle dermal and mesenchymal stem cells
Hair follicle stem cells are similar to mesenchymal stem cells and can become neural-like cells under certain conditions.
research Cyclooxygenases in the skin: pharmacological and toxicological implications
Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.
research Cutaneous Hybrid Cyst in a Sprague-Dawley Rat
A rat had a cyst similar to a hair follicle structure.
research Modulating the stem cell niche for tissue regeneration
Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
research TGF-β family signaling in stem cells
TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
research Control by a hair’s breadth: the role of microRNAs in the skin
MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.
research Steroidogenic factor-1 lineage origin of skin lesions in Carney complex syndrome
Skin lesions in Carney complex are likely caused by a specific group of skin cells that promote pigment production due to a genetic mutation.
research Efficacy of an agonist ofα-MSH, the palmitoyl tetrapeptide-20, in hair pigmentation
Palmitoyl tetrapeptide-20 may help reduce hair greying and increase melanin production.