research Stem Cells and their Niches
The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
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research The aetiology and pathogenesis of alopecia areata
The cause of alopecia areata is likely a mix of genetics, immune system issues, and environmental factors, with more research needed to understand it fully.
research Future Directions in the Treatment of Vitiligo
New treatments for vitiligo may focus on protecting melanocyte stem cells from stress and targeting specific pathways involved in the condition.
research Major approaches of molecular and physiopathological mechanisms for hormonal treatment of melasma: a systematic review
Estrogens and progesterone are key in regulating melasma pigmentation.
research The Peripheral Clock Regulates Human Pigmentation
Certain genes control the color of human hair by affecting pigment production.
research Age-Related Hair Pigment Loss
Graying hair happens due to aging and might be delayed by new treatments.
research Systemic Corticosteroids in Vitiligo
Systemic corticosteroids can help treat rapidly spreading vitiligo but require more research for safer use.
research Vitiligo: A comprehensive overview
Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.
research Age-induced hair greying - the multiple effects of oxidative stress
Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.
research Disseminated Nonsegmental Vitiligo Associated With Halo Nevi and Premature Gray Hair
A rare combination of halo nevi, nonsegmental vitiligo, and early gray hair can occur together.
research Serotoninergic and melatoninergic systems are fully expressed in human skin
Human skin can make serotonin and melatonin.
research Sebocytes are the Key Regulators of Androgen Homeostasis in Human Skin
Sebocytes play a key role in controlling androgen levels in human skin.
research Biology of estrogens in skin: implications for skin aging
Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.
research Identification of hair shaft progenitors that create a niche for hair pigmentation
Scientists found cells in hair that are key for growth and color.
research Cell and Tissue Damage after Skin Exposure to Ionizing Radiation: Short- and Long-Term Effects after a Single and Fractional Doses
Ionizing radiation causes irreversible skin damage, with single doses leading to acute injury and hair graying, and fractional doses causing more severe long-term tissue damage.
research Hair Graying Regulators Beyond Hair Follicle
Hair graying is influenced by factors like nerves, fat cells, and immune cells, not just hair follicles.
research Segmental Vitiligo
Segmental Vitiligo is a stable, early-onset form of vitiligo that responds well to early treatment and is ideal for repigmentation studies.
research Aging and Anti-Aging in Hair and Hair Loss
Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.
research Resident Stem Cell in Skin
Skin stem cells can help improve skin repair and regeneration.
research Performance exploration of multi-gene panels of alopecia areata susceptibility and drug-binding targets
Methotrexate, resveratrol, and curcumin may help treat alopecia areata by targeting immune cells.
research Understanding Cancer Cells of Origin in Cutaneous Tumors
The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.
research Decoding Hyperpigmentation from Biological Mechanisms to Actives with Clinically Proven Topical Efficacy: A Narrative Review
Combining multiple ingredients is the most effective treatment for hyperpigmentation.
research Fractional CO₂ laser combined with topical compound betamethasone for Vitiligo-Associated Leukotrichia: a retrospective study of 13 patients with limited effectiveness
The treatment showed limited success in repigmenting hair for vitiligo-associated leukotrichia.
research Vitiligo: are microbes to blame?
Microbes might play a role in vitiligo.
research In This Issue
Advancements in hair biology include new treatments and tools for hair growth and alopecia.
research Characterization of the serotoninergic system in the C57BL/6 mouse skin
Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.
research Topical Application of a Protein Kinase C Inhibitor Reduces Skin and Hair Pigmentation
Applying a specific inhibitor lightens skin and hair color.
research Pharmacological BACE1 and BACE2 inhibition induces hair depigmentation by inhibiting PMEL17 processing in mice
Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
research Therapeutic Potential of Patient iPSC-Derived iMelanocytes in Autologous Transplantation
Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
research MicroRNAs in the skin: role in development, homoeostasis and regeneration
MicroRNAs are important for skin health and could be targets for new skin disorder treatments.