research Defolliculated (Dfl): A Dominant Mouse Mutation Leading to Poor Sebaceous Gland Differentiation and Total Elimination of Pelage Follicles
The Dfl mutation in mice causes poor sebaceous gland function and complete hair loss.
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990-1000 / 1000+ resultsresearch Current Advanced Therapies Based on Human Mesenchymal Stem Cells for Skin Diseases
Human mesenchymal stem cells show promise for treating skin diseases, but more research is needed to improve treatments.
research Animal and in vitro Models for the Study of Hair Follicles
Understanding hair follicles through various models can help develop new treatments for hair disorders.
research Single-Cell RNA Profiling of Human Skin Reveals Age-Related Loss of Dermal Sheath Cells and Their Contribution to a Juvenile Phenotype
Aging reduces dermal sheath cells, affecting youthful skin appearance.
research Mapping the expression of epithelial hair follicle stem cell‐related transcription factors LHX 2 and SOX 9 in the human hair follicle
LHX2 and SOX9 identify unique hair follicle cell groups, crucial for hair maintenance.
research Hair follicle stem cells:In vitroandin vivoneural differentiation
Hair follicle stem cells can become different cell types and may help treat neurodegenerative disorders.
research Activating β-catenin signaling in CD133-positive dermal papilla cells increases hair inductivity
Boosting β-catenin signaling in certain skin cells can enhance hair growth.
research Altered FGF expression profile in human scalp-derived fibroblasts upon WNT activation: implication of their role to provide folliculogenetic microenvironment
WNT activation in scalp fibroblasts boosts hair growth by increasing FGF9.
research Burn wound and therapeutic challenge
Stem cell therapy could improve burn healing but has challenges to overcome.
research Association of epidemiological and biochemical factors with premature graying of hair: A case–control study
Genetics and nutritional deficiencies are key factors in premature graying of hair.