research Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
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research Montagna Symposium 2015: Harnessing Stem Cells to Reveal Novel Skin Biology and Disease Treatments
The symposium showed that stem cells are key for understanding and treating skin diseases and for developing new skin models and therapies.
research A mouse model of vitiligo based on endogenous auto-reactive CD8 + T cell targeting skin melanocyte
A new mouse model effectively mimics vitiligo for research and drug testing.
research Cell and Tissue Damage after Skin Exposure to Ionizing Radiation: Short- and Long-Term Effects after a Single and Fractional Doses
Ionizing radiation causes irreversible skin damage, with single doses leading to acute injury and hair graying, and fractional doses causing more severe long-term tissue damage.
research Skin melanocytes: biology and development
The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.
research Functionally distinct melanocyte populations revealed by reconstitution of hair follicles in mice
Only skin melanocytes, not other types, can color hair in mice.
research Human Induced Pluripotent Stem Cell–Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo
Human stem cells can help form hair follicles in mice.
research Effect of Procedural-Related Variables on Melanocyte–Keratinocyte Suspension Transplantation in Nonsegmental Stable Vitiligo: A Clinical and Immunocytochemical Study
Different techniques for vitiligo treatment work similarly well, with some better for specific body areas.
research Hardwiring Stem Cell Communication through Tissue Structure
The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.
research Topical RT1640 treatment effectively reverses gray hair and stem cell loss in a mouse model of radiation‐induced canities
RT1640 treatment reverses gray hair and promotes hair growth in mice.
research T-Cell Reconstitution after Thymus Xenotransplantation Induces Hair Depigmentation and Loss
T-cell reconstitution after thymus transplantation can cause hair whitening and loss.
research Low fucosylation defines the glycocalyx of progenitor cells and melanocytes in the human limbal stem cell niche
Low fucosylation boosts stem cell growth in the eye.
research BMP4 regulates differentiation of nestin-positive stem cells into melanocytes
BMP4 helps stem cells turn into pigment-producing cells, affecting hair color and growth.
research Functional and long-lived melanocytes from human pluripotent stem cells with transient ectopic expression of JMJD3
Stem cells can be used to create long-lasting skin cells for treating pigment disorders.
research Diversity of Adult Stem Cell Niches in the Dermal Compartment of Skin
The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
research The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling
Cathepsin L is essential for normal hair growth and development.
research Hair follicles’ transit-amplifying cells govern concurrent dermal adipocyte production through Sonic Hedgehog
Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
research Hair Follicle: A Novel Source of Multipotent Stem Cells for Tissue Engineering and Regenerative Medicine
Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.
research Interaction between stem cell factor and endothelin-1: effects on melanogenesis in human skin xenografts
SCF and ET-1 together significantly increase skin pigmentation and melanin production.
research Single-cell transcriptomics reveals lineage trajectory of human scalp hair follicle and informs mechanisms of hair graying
The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.
research Multipotent nestin‐expressing hair follicle stem cells
Hair follicle stem cells can turn into various cell types and help repair nerves.
research The melanocyte photosensory system in the human skin
Human skin's melanocytes respond to light by changing shape, producing pigments and hormones, which may affect sleep patterns.
research Two novel CreERT2 transgenic mouse lines to study melanocytic cells in vivo
New mouse models help study melanocytic cells for melanoma research.
research The Hair Follicle Stem Cell as the Paradigm Multipotent Adult Stem Cell
Hair follicle stem cells can turn into many cell types and may help repair nerve damage and have other medical uses.
research Convergent Genesis of an Adult Neural Crest-Like Dermal Stem Cell from Distinct Developmental Origins
Skin-derived precursors in hair follicles come from different origins but function similarly.
research Signalling by senescent melanocytes hyperactivates hair growth
Senescent melanocytes can boost hair growth by activating hair stem cells.
research The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis
TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
research Neuropilin 2 expression and function in melanocytes and melanoma
Neuropilin 2 may be a biomarker for melanoma and affects melanocyte behavior.
research Isolation of a Novel Population of Multipotent Adult Stem Cells from Human Hair Follicles
Human hair follicles can provide stem cells for regenerative medicine.
research Adipocytes in Skin Health and Disease
Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.