29 citations
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December 2019 in “Stem Cells Translational Medicine” Fully regenerating human hair follicles not yet achieved.
29 citations
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January 2013 in “International Journal of Medical Sciences” Wnt10b helps hair follicle cells mature and produce pigment.
10 citations
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May 2012 in “PloS one” Low ERCC3 gene activity is linked to non-pigmented hair growth.
6 citations
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September 2022 in “Frontiers in pharmacology” Epimedium extract helps increase skin pigmentation and could be a new treatment for conditions with reduced pigmentation.
1 citations
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January 2014 in “Journal of Cutaneous and Aesthetic Surgery” Regenerative medicine shows promise for aesthetic surgery, but needs more research for widespread use.
October 2024 in “Biology” Dermal papilla cells can help regrow hair and are promising for hair loss treatments.
November 2022 in “Regenerative Therapy” Advancements in tissue engineering show promise for hair follicle regeneration to treat hair loss.
January 2017 in “Springer eBooks” Scientists made working hair follicles using stem cells, helping future hair loss treatments.
277 citations
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July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
132 citations
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June 2016 in “Cell and Tissue Research” The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.
65 citations
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September 2004 in “The American journal of pathology” Blocking BMP signaling causes hair loss and disrupts hair growth cycles.
38 citations
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June 2019 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
31 citations
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January 2021 in “Experimental Dermatology” Skin organoids are a promising new model for studying human skin development and testing treatments.
27 citations
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September 2018 in “Nanomedicine: Nanotechnology, Biology and Medicine” Further research is needed to improve hair regeneration using stem cells and nanomaterials.
15 citations
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January 2018 in “Biomedical Reports” Exosomes are important for skin health and could help diagnose and treat skin diseases.
2 citations
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November 2025 in “Pharmaceutics” Cell-mediated drug delivery systems improve skin disease treatment by using living cells for precise, prolonged, and less toxic therapy.
January 2026 in “BioScience Trends” UV radiation causes skin aging by damaging cells and triggering harmful processes.
December 2025 in “Italian Journal of Anatomy and Embryology” Understanding embryologic layers improves skin disorder diagnosis and supports developing targeted therapies.
PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.
April 2024 in “Frontiers in physiology” Immune cells are crucial for hair growth and preventing hair loss.
February 2024 in “Journal of Investigative Dermatology” Deleting NIPP1 in mouse skin cells causes early aging and chronic skin issues.
Glycyrrhizic acid and licorice extract can significantly reduce unwanted hair growth.
March 2015 in “Plastic and reconstructive surgery” Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
January 2000 in “BioScience” The document concludes that understanding hair biology is key to treating hair disorders, with gene therapy showing potential as a future treatment.
124 citations
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December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
23 citations
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March 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.
9 citations
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December 2013 in “Toxicological Research” Chamaecyparis obtusa oil may help hair grow similarly to minoxidil by affecting certain growth markers and cell factors.
6 citations
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January 2009 in “Elsevier eBooks” The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.
February 2008 in “Experimental dermatology” Oxidative stress plays a significant role in vitiligo, and both skin and non-skin cells may be involved.
1113 citations
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August 1999 in “The New England Journal of Medicine” Hair follicle biology advancements may lead to better hair growth disorder treatments.