20 citations
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April 2019 in “BioMed Research International” Treatments with sunscreen and active ingredients can reduce skin hyperpigmentation by decreasing DNA methylation.
36 citations
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March 2014 in “Biomaterials” A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.
2 citations
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January 1973 in “ACTA HISTOCHEMICA ET CYTOCHEMICA” Brown skin in guinea pigs has more ascorbic acid and related enzymes, black skin uses ascorbic acid well, and white skin has the most protein.
130 citations
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December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle melanocytes die during hair regression.
August 2018 in “Journal of The American Academy of Dermatology” Older men's scalp damage increases with age and sun exposure, a baby girl in the Philippines has Schimmelpenning syndrome, and thyroid screening is advised for children with hair loss and certain risk factors.
11 citations
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April 2013 in “Homo” Darker skin in 10-year-old girls may be an early sign of puberty.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The protein p21 is more abundant in normal skin cells than in melanoma cells and may help protect against melanoma, with UVB light affecting its levels.
114 citations
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April 2004 in “International Journal of Dermatology” Postinflammatory hyperpigmentation causes dark skin patches and needs personalized treatment.
20 citations
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July 2013 in “International Journal of Dermatology” Obesity increases the risk of skin infections, inflammatory conditions, and melanoma, but not basal cell carcinoma.
35 citations
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January 2009 in “Indian Journal of Dermatology, Venereology and Leprology” Older adults commonly experience wrinkles, itchy skin, psoriasis, fungal infections, skin growths, grey hair, hair loss, and nail ridging, but no skin cancer was found in this group.
46 citations
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April 2005 in “Melanoma Research”
58 citations
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February 2016 in “Scientific reports” Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
1 citations
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January 2025 in “Regenerative Biomaterials” Exosomes from Pinctada martensii mucus can safely reduce melanin production, offering a new treatment for skin pigment issues.
2 citations
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July 2022 in “Pediatric dermatology” A toddler with a rash and developmental delays improved after treatment for severe malnutrition caused by a diet lacking in protein.
March 2021 in “Research Society and Development” A blue Staffordshire Bull Terrier had hair loss due to color dilution alopecia, confirmed by tests, but no treatment was pursued.
14 citations
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June 2013 in “Anais Brasileiros de Dermatologia” Follicular red dots may be a normal feature seen in people with less skin pigmentation, not necessarily indicating a scalp disorder.
24 citations
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January 2023 in “Cancer Research” AMPK activation may reduce melanoma risk in red-haired individuals.
July 2019 in “Indian dermatology online journal” Alopecia areata can show unusual red-dotted vessels and dithranol treatment may mask typical patterns.
3 citations
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January 2017 in “Dermatology online journal” Dermoscopy helped diagnose a rare hair disorder in a 2-year-old boy.
October 2019 in “International journal of research in dermatology” Misusing topical corticosteroids can cause skin darkening and other side effects.
56 citations
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November 2010 in “Pigment Cell & Melanoma Research” Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
January 2025 in “International Journal of Dermatology” Better diagnostic tools and treatment guidelines are needed for segmental vitiligo and related pigment issues.
2 citations
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January 2023 in “International journal of biological sciences” Gray hair can potentially be reversed, leading to new treatments.
11 citations
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July 2008 in “International Journal of Dermatology” Greying hairs may be protected from alopecia areata.
November 2025 in “Journal of Investigative Dermatology”
September 2022 in “JAAD case reports” The man has a genetic skin condition called pachyonychia congenita.
7 citations
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September 2024 in “BMC Genomics” Two genes, ERBB4 and ROR1, may cause the unique pigmentation in Lanping black-boned sheep.
Treating vitiligo with stem cells and melanocytes from hair, along with UVB light, works better than without the light.
13 citations
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April 1982 in “The Journal of Dermatology” Poly(ADP-ribose) synthesis is linked to skin cell differentiation.
Acitretin treatment unexpectedly darkened a patient's gray hair.