12 citations
,
September 2022 in “Frontiers in Genetics” Enhancing CD8+ T cell function to induce ferroptosis in tumor cells may help treat skin melanoma.
23 citations
,
June 2015 in “Oncology Letters” Adipose-derived stem cell-conditioned medium can reduce melanoma cell growth and spread.
September 2019 in “Journal of Investigative Dermatology” PCE-DP brightens skin and promotes hair growth by enhancing cell growth and reducing melanin uptake.
127 citations
,
November 2010 in “Pigment cell & melanoma research” We need more research on human hair follicle pigmentation, not just mouse models.
30 citations
,
December 2001 in “Experimental dermatology” Gonadal hormones significantly affect the severity of alopecia areata in mice.
35 citations
,
July 2007 in “Dermatologic clinics” Facial dark spots can be caused by the sun, genetics, makeup, or medicine, and are diagnosed by patient history and skin tests.
September 2025 in “Journal of King Saud University - Science” Lophocereus marginatus extracts may help treat melanoma and stimulate hair growth.
252 citations
,
January 2008 in “Trends in Endocrinology and Metabolism” Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.
Melanocytes can regenerate around hair follicles in bullous pemphigoid, especially in patients with darker skin.
5 citations
,
October 2021 in “Journal of the American Academy of Dermatology” PRAME helps distinguish between benign and malignant skin cells in most cases.
January 2026 in “DR-NTU (Nanyang Technological University)” Human hair melanosomes can be used to create effective, eco-friendly sunscreen.
1 citations
,
November 2023 in “BMC chemistry” Tadalafil and Finasteride may help treat aggressive melanoma.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” A specific group of early-stage melanocytes is reduced in vitiligo-affected skin, which may explain treatment resistance.
27 citations
,
January 1995 Melanin in black hair protects it from sun damage better than light-brown hair.
April 2016 in “Journal of Investigative Dermatology” Mefloquine, an antimalarial drug, is effective in killing melanoma cells resistant to other treatments by causing lethal stress in the cells.
2 citations
,
June 2013 in “In Vitro Cellular & Developmental Biology - Animal” Melanocytes from human fetal hair follicles were successfully cultured, showing potential for hair disease research and clinical use.
12 citations
,
November 2018 in “Archives of Dermatological Research” 49 citations
,
July 2000 in “Journal of Histochemistry & Cytochemistry” POMC-derived peptides are important for skin functions like immune response and stress management.
5 citations
,
June 2011 in “InTech eBooks” High S100B protein levels indicate poor survival in advanced melanoma.
7 citations
,
July 2013 in “Acta Biochimica Polonica” Chemotherapy reduces splenic melanin in mice.
27 citations
,
October 1945 in “Endocrinology” Synthetic hormone treatment reduces melanin and hair growth in rats.
1 citations
,
May 2018 in “International Journal of Molecular Biology Open Access” Hydrogen peroxide is a major risk factor for melanoma in swimmers, more than UV light.
1 citations
,
August 2018 in “Journal of The American Academy of Dermatology” Patients with melanoma who saw dermatologists and were from higher-income areas were more likely to have follow-up visits, which was linked to lower mortality.
1 citations
,
April 2008 in “Pigment Cell & Melanoma Research” Foxn1 is essential for hair pigmentation by directing pigment transfer to hair cells.
1 citations
,
January 2015 in “Journal of Pigmentary Disorders” Melasma is a skin condition linked to female hormones, genetics, UV exposure, and certain medications, but not to pituitary, adrenal, or thyroid diseases.
Melanocyte transplantation can safely restore skin color, especially in stable vitiligo, but must be chosen carefully based on the disease phase.
January 2006 in “Linchuang pifuke zazhi” Stem cell factor and certain proteins help melanocytes from hair follicles move and attach better, aiding vitiligo repigmentation.
1 citations
,
April 2004 in “Cancer” Imatinib mesylate can cause skin lightening, especially in Chinese patients, due to its effect on pigment production.
82 citations
,
March 2013 in “PLoS ONE” Vemurafenib causes skin side effects similar to RASopathies, requiring regular skin checks and UVA protection.
1 citations
,
December 2024 in “Case Reports in Dermatology” Cyclophosphamide likely causes skin darkening by affecting hair follicles.