research Retinoids Modulate MITF: A Novel Mechanism in the Regulation of Melanogenesis - eScholarship
Retinoids can help treat skin pigmentation disorders by affecting melanin production.
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420-450 / 1000+ resultsresearch Perkembangan Aksis Pars Intermedia Hipofise – Melanosit Kulit Monyet Ekor Panjang (Macaca fascicularis).
The PI's development is closely linked to skin and hair pigmentation in macaques.
research Desmoplastic melanoma presenting as primary alopecia neoplastica: a report of two cases
Two women were diagnosed with a rare melanoma that looked like hair loss but was actually a type of skin cancer.
research Retinoids Modulate MITF: A Novel Mechanism in the Regulation of Melanogenesis
Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.
research Endothelin-1 combined with extracellular matrix proteins promotes the adhesion and chemotaxis of amelanotic melanocytes from human hair follicles in vitro
Endothelin-1 helps amelanotic melanocytes stick and move better on certain proteins.
research Detection of Functionally Active Melanocortin Receptors and Evidence for an Immunoregulatory Activity of α-Melanocyte-Stimulating Hormone in Human Dermal Papilla Cells
αMSH may help regulate immune responses in hair follicles and its disruption could lead to hair loss.
research Exosomal miR-222-3p derived from dermal papilla cells inhibits melanogenesis in melanocytes by targeting SOX10 in rabbits
Exosomal miR-222-3p reduces melanin production in rabbits by targeting the SOX10 gene.
research Aberrant Activation of the Hedgehog Pathway in Cutaneous Melanoma: Therapeutic Potential of Pharmacological Inhibitors
Hedgehog pathway inhibitors could be effective in treating melanoma.
research Survival of patchwork melanoblasts is dependent upon their number in the hair follicle at the end of embryogenesis
More melanoblasts in hair follicles mean better survival and proper hair pigmentation.
research An exclusive review of melatonin effects on mammalian melanocytes and melanoma
Melatonin may inhibit melanoma growth and has potential as a cancer therapy aid, but its effects on human skin pigmentation need more research.
research BMI1 is required for melanocyte stem cell maintenance and hair pigmentation
BMI1 is essential for preventing hair greying and maintaining hair color.
research Editor's evaluation: Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma
Keratinocytes can reduce the survival of certain melanoma cells, suggesting new therapy paths.
research Therapeutic Potential of Patient iPSC-Derived iMelanocytes in Autologous Transplantation
Patient-derived stem cell melanocytes could be a promising treatment for vitiligo.
research Perifollicular Melanocyte Regeneration in Bullous Pemphigoid
Melanocytes can regenerate around hair follicles in bullous pemphigoid, especially in patients with darker skin.
research RAGE and Its Ligands in Melanoma
RAGE is a potential target for melanoma treatment, but its effectiveness is uncertain due to variable expression levels.
research Overexpression of hepatoma-derived growth factor in melanocytes does not lead to oncogenic transformation
Overexpression of HDGF in melanocytes does not cause cancer.
research Observation of cultured amelanotic melanocytes from hair follicles by atomic force microscopy
Amelanotic melanocytes from hair follicles are immature and likely don't transfer melanosomes to keratinocytes.
research BH05 (P049) Best foot forward: awareness of melanoma of the foot among podiatrists
Podiatrists need more training to detect foot melanoma early.
research Giant pigmented tumour of the scalp—a diffuse neurofibroma or a congenital naevus showing neurofibromatous changes? Immunohistochemical and electron microscopic studies
The tumor likely shows dual neural crest differentiation.
research Hair melanocytes as neuro-endocrine sensors—Pigments for our imagination
Hair melanocytes help the skin respond to stress and regulate hair pigmentation.
research 014 Non-melanoma skin cancer in skin of color: Cases of mistaken identity
Non-melanoma skin cancer in darker-skinned people can be misdiagnosed, so doctors need to be more aware to diagnose it correctly and early.
research Subclinical speckled perifollicular melanosis of the scalp.
The scalp has a natural speckled pattern of increased pigment around hair follicles, possibly linked to local hormone production.
research Clinical, Dermoscopic, and Histological Characteristics of Melanoma Patients According to the Age Groups: A Retrospective Observational Study
Melanoma characteristics vary by age, which could help doctors with diagnosis and prevention.
research Skin precancer.
Sun exposure and genetics increase skin cancer risk from precancerous lesions.
research Molecular mapping of lymph node metastases by real-time reverse transcription polymerase chain reaction in two melanoma patients
The conclusion is that a certain test might help find cancer spread in lymph nodes for melanoma patients, but more research is needed due to false positives.
research Proopiomelanocortin expression in the skin during induced hair growth in mice
research Desmoplastic melanoma presenting as an alopecic patch in a young patient
A man had a rare skin cancer that looked like a bald spot.
research Tfap2b specifies an embryonic melanocyte stem cell that retains adult multi-fate potential
The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.
research The Hair Pigmentation Unit and Hair Graying
Hair color is due to active pigment cells in hair during growth.
research Expression of melanocortin receptors on cutaneous fibroblastic cells – collagen and beyond
MC-1R in skin cells may influence inflammation and collagen production.