January 2017 in “Archives of clinical and biomedical research” Enhancing melanin's energy generation may help treat alopecia areata.
16 citations
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September 1999 in “Journal of Investigative Dermatology Symposium Proceedings” 59 citations
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March 2003 in “The Lancet” Imatinib can repigment grey hair, while SU11428 can cause temporary hair depigmentation.
35 citations
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January 1981
36 citations
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March 2014 in “Biomaterials” A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.
68 citations
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March 2008 in “Experimental dermatology” The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.
The human scalp has different types of pigment cells in hair follicles with varying abilities to produce pigment.
14 citations
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April 2005 in “Experimental Dermatology” Stressed fibroblasts greatly increase melanin production in hair, skin, and eye cells, mainly due to a growth factor called bFGF.
9 citations
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May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Human melanocytes have unique traits that affect melanoma development and prognosis.
1 citations
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September 2004 in “Experimental Dermatology” MC-1R is present in skin cells and may help reduce inflammation.
61 citations
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June 2018 in “Proceedings of the National Academy of Sciences of the United States of America” Light can turn on hair growth cells through a nerve path starting in the eyes.
March 2024 in “GSC Advanced Research and Reviews” Different light affects cell functions and can help treat skin conditions.
January 2021 in “Journal of clinical and cosmetic dermatology” Human skin responds to light with protective mechanisms, but more research is needed to understand these processes and their implications for health and therapy.
April 2018 in “Journal of Investigative Dermatology” The keratin network in mouse skin changes during cornification and affects the skin's protective barrier.
April 2018 in “Journal of Investigative Dermatology” STIM1 is essential for sweat secretion.
April 2018 in “Journal of Investigative Dermatology” Researchers found a substance in chicken egg yolk that helps hair grow.
April 2018 in “Journal of Investigative Dermatology” Light can activate hair growth through a pathway from the eyes to hair follicles.
April 2018 in “Journal of Investigative Dermatology” People with alopecia areata have higher levels of a heart disease marker in their blood.
April 2018 in “Journal of Investigative Dermatology” Sensitive scalp has higher pH, more redness, abnormal sebum, and altered bacterial makeup.
450 citations
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January 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color is determined by melanin produced and transferred in hair follicles.
86 citations
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August 2000 in “Pigment cell research” Melanocyte activity in hair follicles is linked to the hair growth cycle, being active in growth phases and inactive in rest phases.
13 citations
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April 2022 in “Frontiers in oncology” Melanoma development can be linked to the breakdown of skin's melanin-producing units.
Adenophora Radix extract can promote hair growth and increase melanin in mice.
May 2004 in “International Journal of Cosmetic Science” Melanogenesis inhibitors like kojic acid and niacinamide can reduce inflammation and pigment production in skin cells.
20 citations
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December 2013 in “PubMed” Quercetin boosts melanin production in mouse hair follicles.
84 citations
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April 2005 in “Dermatologic Clinics” Treatments for melanin disorders exist, but more effective options needed.
3 citations
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November 2023 in “Frontiers in cell and developmental biology” Melanocytes are important for skin and hair color and protect the skin from UV damage.
Melanin-rich skin has unique challenges in diagnosing and treating skin diseases.
7 citations
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August 2013 in “Experimental and Therapeutic Medicine” 1,25-dihydroxyvitamin D3 helps melanocyte precursors from hair follicles grow and produce melanin, aiding vitiligo treatment understanding.
The PI's development is closely linked to skin and hair pigmentation in macaques.