The PI's development is closely linked to skin and hair pigmentation in macaques.
January 2008 in “Deep Blue (University of Michigan)” Wnt signaling is crucial for Hedgehog-driven skin tumor growth.
February 2005 in “CRC Press eBooks” Hair color is due to active pigment cells in hair during growth.
June 2004 in “Journal of Investigative Dermatology” Increased pigmentation may protect skin from UVB, new targets for skin disease treatments were identified, sunscreen ingredients don't affect hormones, TNF-α inhibitors may help diabetic wounds, and certain treatments could prevent chemotherapy-induced hair loss.
January 2004 in “Linchuang pifuke zazhi” All-trans retinoic acid helps amelanotic melanocytes in hair follicles develop and produce pigment while reducing their growth.
January 1990 in “Springer eBooks” Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.
April 1986 in “CRC Press eBooks” Hair color is determined by melanins produced in hair cells.
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January 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color is determined by melanin produced and transferred in hair follicles.
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January 2009 in “Journal of Investigative Dermatology” UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.
Polygonum multiflorum, especially emodin, may help treat hair loss by targeting specific proteins, offering a new approach beyond traditional therapies.
April 2024 in “Histochemistry and cell biology” N-acetylcysteine may prevent hair loss caused by chemotherapy.
December 2021 in “Dermatology research” Low levels of vitamin B12, ferritin, and calcium are linked to premature graying of hair.
May 2021 in “GSC Advanced Research and Reviews” Hair color is influenced by genetics and can indicate certain health conditions.
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June 2012 in “PloS one” A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.
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July 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” Light affects skin health, aging, and cancer risk, and new light-based treatments and imaging are promising for skin care.
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June 2025 in “Pigment Cell & Melanoma Research” SASH1 gene mutations are linked to various inherited skin pigmentation disorders.
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November 2015 in “Phytotherapy Research” Certain herbal compounds, especially from bitter melon, can inhibit cancer growth and promote hair growth by blocking PAK1.
September 2004 in “Experimental dermatology” Melatonin directly affects mouse hair follicles and may influence hair growth.
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January 1997 in “Forensic science international” Drugs can be incorporated into hair based on their chemical properties and hair pigmentation.
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June 2019 in “BMC Genomics” lncRNAs significantly influence koi carp skin color.
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December 2014 in “Dermatologica sinica/Zhōnghuá pífūkē yīxué zázhì” Keratinocytes control how melanocytes work.
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November 2019 in “PLoS ONE” MED23 and GNAQ genes are crucial for chicken feather color.
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February 2023 in “Genes” lncRNAs influence cashmere fiber traits like diameter and color in goats.
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January 2019 in “Indian Journal of Pharmacology” Melitane 5% and hair supplements improved hair color in a 14-year-old with early graying.
Metformin shows promise for treating skin conditions, but more research is needed.
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November 2017 in “Medical Sciences” Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.
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November 2022 in “Frontiers in Oncology” Melanin may help melanoma cells grow by aiding their metabolism.
January 2005 in “Enlighten: Publications (The University of Glasgow)” Melanocyte pathology requires keratinocyte hyperplasia and regulation dysfunction.
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March 1998 in “Journal of Investigative Dermatology” The transgene likely activated an oncogene or interrupted a tumor suppressor gene, causing melanoma in mice.
January 1999 in “Praxis sociológica” Melanocyte stem cells can become melanoma, resembling human melanoma.