18 citations
,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
August 2009 in “International Journal of Dermatology” A postmenopausal woman's facial redness, acne, and excess hair were caused by too much hormone therapy for insomnia, but improved after stopping the treatment.
21 citations
,
April 2016 in “International Journal of Oncology” GnRH treatment can reduce breast cancer cell invasion.
Melatonin increased the activity of a hair growth gene in Cashmere goats.
13 citations
,
July 2012 in “Pigment Cell & Melanoma Research” A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
10 citations
,
May 2012 in “PloS one” Low ERCC3 gene activity is linked to non-pigmented hair growth.
44 citations
,
July 2012 in “Endocrine Practice” We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.
August 2006 in “Experimental dermatology” Neurotrophins are important for hair growth and response to stress.
April 2023 in “Tropical Animal Health and Production” Giving melatonin to sheep before the non-breeding season can improve their chances of reproducing in northwest Mexico.
November 2025 in “Journal of Investigative Dermatology” TEC kinases may help cause inflammation in vitiligo and could be targeted for treatment.
December 2022 in “Cureus” Hormones significantly influence hair growth, with conditions like hirsutism and patterned hair loss linked to hormone levels; more research is needed for full understanding.
The microenvironment affects the behavior and survival of melanocytes with the GNAQ oncogene in melanoma.
28 citations
,
November 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” GMG-43AC may help reduce unwanted hair growth and treat certain hair loss conditions.
39 citations
,
April 2001 in “Journal of The American Academy of Dermatology” Latanoprost, a glaucoma medication, caused excessive eyelid hair growth in many patients.
August 2007 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Overexpression of a specific receptor in mice skin causes skin thinning, early skin barrier formation, eye issues, and hair loss.
17 citations
,
April 2002 in “Contact Dermatitis” Minoxidil 5% caused skin discoloration in a man using it for hair loss.
Delta-opioid receptors affect skin cell circadian rhythms, possibly impacting wound healing and cancer.
January 2008 in “Springer eBooks” Thyroid hormone may be useful for treating various skin conditions and needs more research.
64 citations
,
March 2005 in “Journal of Investigative Dermatology” Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.
6 citations
,
August 2022 in “Journal of Herbal Medicine” Mangosteen extract may help with hair growth and prevent graying.
25 citations
,
May 2018 in “Clinical & Translational Oncology” New melanoma treatments can cause skin side effects, including skin cancer and rashes, but combining treatments may reduce these risks.
Skin cells can naturally limit the growth of cancerous changes by balancing cell renewal and differentiation.
September 2022 in “Journal of medical sciences and health” A person had two different benign skin tumors, a trichoadenoma and melanocytic naevi, at the same time but in different places on the face.
11 citations
,
November 1991 in “Journal of Neuropathology & Experimental Neurology” Brindled mice show abnormal catecholamine neuron development due to copper deficiency.
Multiphoton microscopy helps understand and improve vitiligo treatments by visualizing skin cell changes.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” MPZL3 is important for controlling the hair growth cycle in mice and humans.
April 2023 in “Journal of Investigative Dermatology” A protein called MPZL3 in mitochondria slows down hair growth and could be a target for treating hair growth disorders.
20 citations
,
January 2019 in “Journal of dermatological science” Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.
13 citations
,
November 2021 in “Frontiers in Immunology” Melatonin could be an effective treatment for Alzheimer's Disease and rosacea.
1 citations
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July 2023 in “Journal of Biophotonics” Red light at 8 mW/cm2 most effectively promotes hair cell growth and affects key growth pathways, especially in cells treated with a hair loss-related hormone.