research ESGCT and FSGT Collaborative Congress Helsinki, Finland September 17–20, 2015 Abstracts
The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.
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research Scaffolds for epithelial and hair follicle regeneration
Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.
research Functional Hair Follicle Regeneration
Scientists made working hair follicles using stem cells, helping future hair loss treatments.
research Tuning Wnt Signals for More or Fewer Hairs
Changing Wnt signaling can lead to more or less hair growth and might help treat hair loss and skin conditions.
research Modulating embryonic signaling pathways paves the way for regeneration in wound healing
Modifying certain signals in the body can help wounds heal without scars and regrow hair.
research Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth
Growing human skin cells in a 3D environment can stimulate new hair growth.
research Comparative regenerative mechanisms across different mammalian tissues
Understanding different species' regeneration can improve mammalian healing.
research Morpho-Regulation of Ectodermal Organs
Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
research Cells within the bulge region of mouse hair follicle transiently proliferate during early anagen: heterogeneity and functional differences of various hair cycles
Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.
research Local circadian clock gates cell cycle progression of transient amplifying cells during regenerative hair cycling
Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.
research Development and Homeostasis of the Skin Epidermis
The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
research YAP and TAZ are essential for basal and squamous cell carcinoma initiation
YAP and TAZ proteins are necessary for the development of two types of skin cancer.
research Defining Hair Follicles in the Age of Stem Cell Bioengineering
The study found that bioengineered hair follicles work when using cells from the same species but have issues when combining human and mouse cells.
research Single‐cell transcriptomic analysis of small and large wounds reveals the distinct spatial organization of regenerative fibroblasts
Different types of skin cells are organized in a special way in large wounds to help with healing and hair growth.
research Tissue engineering strategies for human hair follicle regeneration: How far from a hairy goal?
Fully regenerating human hair follicles not yet achieved.
research Skin-derived stem cells as a source of primordial germ cell- and oocyte-like cells
Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.
research Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice
Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.
research Hes1 regulates anagen initiation and hair follicle regeneration through modulation of hedgehog signaling
Hes1 protein is important for hair growth and regeneration, and could be a potential treatment for hair loss.
research Pannexin 3 regulates skin development via Epiprofin
Pannexin 3 helps skin and hair growth by controlling a protein called Epiprofin.
research Autoantigen Discovery in the Hair Loss Disorder, Alopecia Areata: Implication of Post-Translational Modifications
New protein changes may be involved in the immune attack on hair follicles in alopecia areata.
research Recreation of a hair follicle regenerative microenvironment: Successes and pitfalls
Hair growth environment recreated with challenges; stem cells make successful skin organoids.
research Transcriptome analyses of reprogrammed feather / scale chimeric explants revealed co-expressed epithelial gene networks during organ specification
Key genes can rewire networks, changing skin appendage types.
research Single-cell transcriptomics defines keratinocyte differentiation in avian scutate scales
The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.
research Detecting the Mechanism behind the Transition from Fixed Two-Dimensional Patterned Sika Deer (Cervus nippon) Dermal Papilla Cells to Three-Dimensional Pattern
The study concluded that changing the culture conditions can cause sika deer skin cells to switch from a flat to a 3D pattern, which is important for creating hair follicles.
research Knockout of p16INK4a promotes aggregative growth of dermal papilla cells
Removing p16INK4a from skin cells can lead to faster and more clumped growth, which might help with hair growth.
research SOX2 in the Skin
SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.
research 915 Dietary grape powder inhibits atopic dermatitis-like skin lesions in NC/Nga mice
Eating grape powder may reduce the severity of skin allergy symptoms.
research 916 Gynecologic and hormonal comorbidities of scarring alopecia: A retrospective review
Women with scarring alopecia are less likely to have used hormone replacement therapy or oral contraceptives compared to those with female pattern hair loss.
research Molecular Regulation and Cellular Heterogeneity in Skin Repair and Hair Follicle Regeneration
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
research Hair follicles, their disorders and their opportunities
Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.