research The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle
CDP is crucial for lung and hair follicle cell development.
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930-960 / 1000+ results research Oncogenic Kras induces spatiotemporally specific tissue deformation through converting pulsatile into sustained ERK activation
research Author response: Smad4 restricts differentiation to promote expansion of satellite cell derived progenitors during skeletal muscle regeneration
SMAD4 is crucial for muscle repair in young adults but not in aged mice.
research A new look into an old problem: keratins as tools to investigate determination, morphogenesis, and differentiation in skin.
Keratin expression reflects cell organization and differentiation, not causes it.
research Identification and dissection of an enhancer controlling epithelial gene expression in skin
A specific DNA region controls skin cell gene expression by working with certain proteins.
research The Localization of Label-Retaining Cells in Eccrine Glands
Stem cells in eccrine glands could be used for regenerative medicine.
research 320 Desmoglein 3-mediated mechanical transadhesion controls epithelial stem cell quiescence
Desmoglein 3 is important for keeping hair follicle stem cells inactive and maintaining their special properties.
research Enhanced Differentiation Potential of Pigmented Human Epidermal Equivalents
PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.
research Epidermal Notch signalling: differentiation, cancer and adhesion
Notch signalling helps skin cells differentiate and prevents tumors.
research Author response: Hair follicle dermal condensation forms via Fgf20 primed cell cycle exit, cell motility, and aggregation
Fgf20 helps form hair follicle structures by stopping cell division and increasing cell movement.
research Repeal and Replace: Adipocyte Regeneration in Wound Repair
Skin wounds can create fat cells that help regenerate hair follicles, with BMP signaling playing a crucial role in this process.
research 1330 Flexible fate determination ensures robust differentiation in the skin hair follicle
Hair follicle stem cells can change their role to ensure proper hair development.
research In vivo effects of epidermal growth factor on epidermal pattern formation and hair follicle initiation in the marsupial bandicoot Isoodon macrourus
Epidermal growth factor disrupts hair and gland formation in bandicoots.
research Engineered building bloks to print endogenous tissue and complex organs in vitro
New bio-ink can print complex tissues and organs.
research Mesenchymal stem cells in periodontics: new perspectives
Tooth-derived stem cells show promise for regenerating gum tissue but need standardized selection methods.
research Interfollicular epidermal stem-like cells for the recreation of the hair follicle epithelial compartment
Human skin cells with stem-like features can help create new hair follicles and sebaceous glands when combined with other cells.
research Review: Evolution and diversification of corneous beta‐proteins, the characteristic epidermal proteins of reptiles and birds
Corneous beta-proteins evolved uniquely in reptiles and birds, forming scales, claws, beaks, and feathers.
research Neuregulin3 alters cell fate in the epidermis and mammary gland
Neuregulin3 affects cell development in the skin and mammary glands.
research Dermal‐Epidermal Cross‐Talk: Differential Interactions With Microvascular Endothelial Cells
Human dermal fibroblasts help microvascular endothelial cells grow, but not vice versa.
research Author response: Interplay of opposing fate choices stalls oncogenic growth in murine skin epithelium
The balance between cell renewal and differentiation controls the growth of cancerous cells in mouse skin.
research Decellularized Wharton's jelly matrix as a three dimensional scaffold for wound healing and hair regeneration applications
Using Wharton's jelly stem cells and scaffolds can help regenerate skin and hair.
research Rare Gli1+ perivascular fibroblasts promote skin wound repair
Rare Gli1+ fibroblasts are crucial for skin wound healing.
research A Simple In Vivo System for Studying Epithelialization, Hair Follicle Formation, and Invasion Using Primary Epidermal Cells from Wild-Type and Transgenic Ornithine Decarboxylase-Overexpressing Mouse Skin
Overexpressing ornithine decarboxylase and v-Ha-ras in keratinocytes leads to invasiveness and malignancy.
research Investigating the role of notch ligands regulating epidermal stem cell differentiation
research Disruption of the temporally regulated cloaca endodermal β-catenin signaling causes anorectal malformations
Disrupting β-catenin signaling in certain cells causes anorectal malformations.
research Bone‐forming cells with pronounced spread into the third dimension in polymer scaffolds fabricated by two‐photon polymerization
Bone-forming cells grow well in 3D polymer scaffolds with 35 µm pores.
research APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex
A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.
research Approach to the adult female patient with diffuse nonscarring alopecia
The document concludes that careful evaluation is key to diagnose and treat women with hair loss, with tests for thyroid, iron, and hormones as needed.
research Optimal Management of Hair Loss (Alopecia) in Children
Effective management of children's hair loss involves accurate diagnosis, various treatments, and supportive care.
research Idiopathic Hirsutism*
The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.