January 2006 in “Zhonghua miniao waike zazhi” Finasteride can reliably cause hypospadias in rabbits.
9 citations
,
April 2010 in “The Journal of Dermatology” Nestin helps identify certain melanoma cells in nodular melanoma.
694 citations
,
April 2000 in “Nature genetics” Msx2 deficiency in mice leads to bone growth and organ development problems.
53 citations
,
July 2002 in “Journal of Investigative Dermatology” The Dfl mutation in mice causes poor sebaceous gland function and complete hair loss.
Finasteride affects prostate development differently in male and female Mongolian gerbils.
April 2013 in “The Journal of Urology” Researchers created a simple tool to predict bladder blockage from prostate enlargement using urine flow rate and prostate volume.
April 2023 in “Journal of Investigative Dermatology” Ectomesenchyme is a key source of skin stem cells.
96 citations
,
September 1996 in “PubMed” Desmocollin 1 and 3 have distinct patterns in human tissues, with Dsc1 in specific skin and hair layers and Dsc3 in various epithelial layers.
1 citations
,
July 2017 in “Cancer Research” Overexpressing NSD3 in mice causes breast cancer-like tumors and gland abnormalities.
9 citations
,
October 1994 in “Brain Research” Fetal sheep develop skin nerve pathways and responses to touch and heat between 75 and 134 days of gestation.
11 citations
,
June 2010 in “Medical Molecular Morphology” 54 citations
,
October 2007 in “The FASEB Journal” Phospholipase C-δ1 is crucial for normal hair development.
9 citations
,
September 2022 in “Journal of Clinical Investigation” Replacing defective mesenchymal cells with normal ones fixes thymic growth issues in 22q11.2DS mouse models.
April 2025 in “The Indian Journal of Animal Reproduction” Testicular abnormalities in dogs should be treated to prevent complications like seminoma.
59 citations
,
March 1984 in “Journal of Investigative Dermatology”
September 2022 in “Annals of medicine and surgery” Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.
1 citations
,
October 2020 in “Research Square (Research Square)” Abnormal Wnt signaling in hair follicle stem cells can lead to acne-like cysts.
7 citations
,
August 2012 in “The Journal of Urology” Women with congenital adrenal hyperplasia showed no prostatic growth.
January 2024 in “Wiadomości Lekarskie” Ancient immune and signaling pathways still regulate blood cell development.
December 2024 in “European journal of medical research” 25 citations
,
October 2000 in “Gene” Gene regulatory regions evolve faster than protein coding regions, allowing new gene relationships without changing transcription factors.
December 2004 in “PLoS ONE” The Foxn1(-/-) phenotype disrupts hair growth and affects skin stem cells.
297 citations
,
January 2002 in “Development” Overexpression of ΔNLef1 in mouse skin leads to hair loss, cysts, and skin tumors.
1 citations
,
November 2023 in “Chemical and Biological Technologies in Agriculture” JUNB boosts hair growth in goats by helping specific skin cells multiply.
December 2021 in “Journal of Investigative Dermatology” Neutrophils quickly move to the site of skin injury.
30 citations
,
November 2018 in “EMBO Reports” The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.
54 citations
,
November 1995 in “The Journal of Clinical Endocrinology & Metabolism” Females with 5 alpha-reductase-2 deficiency have less body hair, no acne, normal fertility, and delayed menarche.
2 citations
,
February 2020 in “Journal of Investigative Surgery” Flutamide-induced hypospadias in rats slows down early wound healing.
6 citations
,
January 2025 in “Differentiation” WNT10A is important for tissue development and linked to various human disorders.
March 2025 in “American Journal of Medical Genetics Part A” A rare genetic variant linked to skin cysts was found in blood DNA, suggesting its role in cyst formation.