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New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Some people have a genetic variation that makes them less effective at breaking down drugs.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Melatonin may help whisker growth in mice.

MitoQ may help treat hair loss by boosting hair growth pathways.

Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.

Lysophosphatidic acid affects sensory neurons and may cause neuropathic pain and itch.

XEDAR deficiency prevents muscle degeneration in EDA-A2 transgenic mice.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

Glioblastoma cells can make androgens, which might help the tumor grow.

The vitamin D receptor can affect gene activity even without its usual hormone in hair and skin.

LPAR6 has a unique way of binding and activating, which helps in designing treatments for hair loss and cancer.

A specific molecular switch, driven by MAPK/ERK signaling, helps spiny mice heal wounds by regenerating skin instead of forming scars.

αMSH may help regulate immune responses in hair follicles and its disruption could lead to hair loss.

The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.

PROTACs offer new ways to treat hard-to-target diseases, with promising drugs for cancer in advanced trials.

A new sensor can detect minoxidil accurately and effectively.

TRPV4 slows hair growth by affecting hair follicle cells.

GLI2 increases follistatin production in human skin cells.

A patient with a nerve disorder died from infection complications after developing insulin resistance from a treatment.

The PTGER2 gene is highly active in Cashmere goat skin and its activity changes with the hair growth cycle.

Androgen receptor activity is influenced by hormones, co-factors, modifications, and mutations.

Lack of TG2 increases fat storage and lowers cell cleanup in skin oil cells.

EGFRi/MEKi treatments cause hair follicles to lose some immune protection, leading to inflammation.

MEX3A is crucial for maintaining intestinal stem cells in mice.

Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.

Mast cell and nerve fiber interactions in mouse skin change with the hair cycle.

Keratinocytes can reverse the effects of the GNAQ oncogene, inhibiting melanoma cell growth.