Boosting certain cell signals can prevent hair loss from chemotherapy and radiation.
14 citations
,
December 1998 in “The Journal of Clinical Endocrinology and Metabolism” MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.
72 citations
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July 2012 in “Journal of Investigative Dermatology” Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
2 citations
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December 2022 in “Scientific Data” The study maps how genes are regulated during mouse hair growth.
32 citations
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February 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.
32 citations
,
December 1969 in “The Lancet” Children with marasmus have more resting hair follicles and thinner, less pigmented hair, showing long-term malnutrition.
Introducing the OTC gene improved symptoms in mice with OTC deficiency.
1 citations
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September 2013 in “PubMed” Methotrexate therapy for psoriasis may help regrow hair in some cases of male pattern baldness.
65 citations
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August 2007 in “Experimental Dermatology” Human hair follicles can make and process prostaglandins, which may affect hair growth.
61 citations
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April 2013 in “PloS one” The study found key genes and pathways involved in cashmere goat hair growth stages.
September 2014 in “Journal of the American Academy of Dermatology” The girl likely has Loose anagen hair syndrome, which may improve on its own or with minoxidil.
6 citations
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October 1988 in “Clinics in Dermatology” The molecular details of hair growth are not well understood.
1 citations
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August 2016 in “Dermatology - Open Journal” Mitochondria change shape to meet energy needs during cell movement.
March 2009 in “Dermatology Online Journal” Manipulating EGFR signaling may help treat hair loss and promote hair growth.
January 2023 in “Advanced Biology” DNA methylation changes affect gene expression during esophageal healing with silk grafts in rats.
41 citations
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December 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” Deleting MED1 in skin cells causes hair loss and skin changes.
67 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Chronic Telogen Effluvium may resolve after years and is diagnosed by examining the patient's history and clinical signs, with treatment aimed at underlying causes and possibly minoxidil.
June 2021 in “Research Square (Research Square)” Melatonin can increase cashmere yield by altering gene expression and restarting the growth cycle early.
1 citations
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February 2016 in “Cell Transplantation” Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.
4 citations
,
March 2007 in “British Journal of Dermatology” Gefitinib therapy can cause unusual hair growth on the nose.
990 citations
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October 1999 in “Development” Activated LEF/TCF complexes are crucial for hair development and cycling.
January 2007 in “E-Deusto: conocimiento para ir por delante” The study provided insights into burn healing and scarring, aiding future treatment development.
94 citations
,
February 1994 in “The journal of investigative dermatology/Journal of investigative dermatology” EGF makes hair follicles grow longer but stops hair production.
7 citations
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May 2017 in “Behavioural brain research” Changing neuroactive steroid levels early in life can affect how adult rats respond to alcohol's stimulating effects.
August 2024 in “Biomolecules & Therapeutics” A new compound, HTPI, promotes hair growth by protecting cells from damage and regulating energy use.
November 2025 in “Journal of Investigative Dermatology” Estetrol may help prevent hair loss and support hair growth in women.
November 2024 in “Journal of Investigative Dermatology” TGF-β signaling is essential for new hair growth after wounds.
119 citations
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November 1969 in “Journal of Ultrastructure Research” Macrophages help break down collagen around hair follicles during hair growth.
29 citations
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March 2015 in “Journal of Investigative Dermatology” Cyclosporine A promotes hair growth and prolongs the active growth phase in human hair follicles, but may work differently than in rodents.
September 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Non-invasive methods can effectively monitor hair growth cycles, aiding hair loss treatment development.