research From regenerative dentistry to regenerative medicine: progress, challenges, and potential applications of oral stem cells
Oral stem cells show promise for tissue repair, but more human trials are needed.
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960-990 / 1000+ resultsresearch Delineation of Matriptase Protein Expression by Enzymatic Gene Trapping Suggests Diverging Roles in Barrier Function, Hair Formation, and Squamous Cell Carcinogenesis
Matriptase is crucial for skin barrier, hair growth, and may contribute to skin cancer.
research Fluorescence Microscopy—An Outline of Hardware, Biological Handling, and Fluorophore Considerations
Designing effective fluorescence microscopy experiments requires careful consideration of hardware, biological models, and imaging agents.
research Challenges in the Physical Characterization of Lipid Nanoparticles
Characterizing lipid nanoparticles is challenging due to issues with sensitivity, reproducibility, and reliability.
research Syndecan-1 Is Required to Maintain Intradermal Fat and Prevent Cold Stress
Syndecan-1 is essential for maintaining skin fat and preventing cold stress.
research p63 Regulates Human Keratinocyte Proliferation via MYC-regulated Gene Network and Differentiation Commitment through Cell Adhesion-related Gene Network
p63 is essential for skin cell growth and differentiation by controlling specific gene networks.
research Design and fabrication of customizable microneedles enabled by 3D printing for biomedical applications
3D-printed microneedles improve drug delivery and diagnostics but face scalability and regulatory challenges.
research Environmental Air Pollutants Affecting Skin Functions with Systemic Implications
Air pollution harms skin health and can worsen skin diseases.
research The Potential of Ginkgo biloba as a Source of Biologically Active Compounds—A Review of the Recent Literature and Patents
Ginkgo biloba has health benefits but also contains toxic compounds, driving interest in its use in medicine and food.
research Organoid technology for tissue engineering
Organoid technology helps create mini-organs for studying diseases and testing drugs.
research Medicinal Chemistry of Drugs with N-Oxide Functionalities
N-oxides are important in medicine for improving drug properties and targeting.
research Functional Food Nutrients, Redox Resilience Signaling and Neurosteroids for Brain Health
Functional foods and nutrients like flavonoids, vitamin D, omega-3s, and probiotics can boost brain health and reduce stress.
research Overview of Caffeine Effects on Human Health and Emerging Delivery Strategies
Caffeine can boost health, prevent diseases, and improve performance, with new methods enhancing its benefits.
research An Overview of the Health Benefits, Extraction Methods and Improving the Properties of Pomegranate
Pomegranate has health benefits and new methods are improving its use in supplements.
research Furnishing Wound Repair by the Subcutaneous Fascia
The subcutaneous fascia is key to fast wound healing and could improve treatments for chronic wounds and scarring.
research Frontal fibrosing alopecia: An update on the hypothesis of pathogenesis and treatment
The document concluded that more research is needed to find the best treatment for Frontal fibrosing alopecia.
research Gene therapy to enhance angiogenesis in chronic wounds
Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.
research Hypoxia in Cell Reprogramming and the Epigenetic Regulations
Hypoxia and epigenetics are crucial for cell growth and tissue regeneration.
research Gab1 and Mapk Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence
Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.
research Formononetin: A Pathway to Protect Neurons
Formononetin may help protect the brain and treat neurological diseases.
research CXCL12+ dermal fibroblasts promote neutrophil recruitment and host defense by recognition of IL-17
CXCL12+ fibroblasts help recruit neutrophils to fight skin infections.
research Transplanted hair follicle stem cells migrate to the penumbra and express neural markers in a rat model of cerebral ischaemia/reperfusion
Hair follicle stem cells may help repair the brain after a stroke.
research The Aldo-Keto Reductase AKR1B10 Is Up-Regulated in Keloid Epidermis, Implicating Retinoic Acid Pathway Dysregulation in the Pathogenesis of Keloid Disease
The study found that the enzyme AKR1B10 was significantly up-regulated in keloid epidermis, suggesting a link between retinoic acid pathway dysregulation and keloid disease pathogenesis. Overexpression of AKR1B10 in normal keratinocytes mimicked the retinoic acid pathway changes seen in keloid epidermis, supporting the hypothesis that AKR1B10 contributes to keloid formation by promoting a profibrotic profile. The research highlighted the potential of targeting AKR1B10 as a therapeutic approach for keloid disease, as current retinoic acid treatments were only partially effective. The study emphasized the importance of epithelial-mesenchymal interactions and suggested that AKR1B10-selective inhibitors could be promising treatments.
research Microneedles as a Promising Technology for Disease Monitoring and Drug Delivery: A Review
Microneedles are promising for disease monitoring and drug delivery due to their minimal invasiveness and versatility.
research Modulating the Antioxidant Response for Better Oxidative Stress-Inducing Therapies: How to Take Advantage of Two Sides of the Same Medal?
Enhancing antioxidant responses can improve treatments for various diseases.
research Formulation and Evaluation of PLGA Nanoparticulate-Based Microneedle System for Potential Treatment of Neurological Diseases
The microneedle system shows promise for non-invasive brain drug delivery.
research Effect of composite biodegradable biomaterials on wound healing in diabetes
Composite biodegradable biomaterials can improve diabetic wound healing but need more development for clinical use.
research Hair follicle stem cells as a skin‐organizing signaling center during adult homeostasis
Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
research Unveiling the Potential of Single‐Cell Encapsulation in Biomedical Applications: Current Advances and Future Perspectives
Single-cell encapsulation shows promise for medical use but faces production challenges.
research Exogeneous metal ions as therapeutic agents in cardiovascular disease and their delivery strategies
Metal ions can help treat heart diseases by protecting cells and repairing tissues.