82 citations
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May 2009 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Caffeine penetrates human skin in lab tests similarly to real-life conditions, but actual skin use is still essential for accurate results.
82 citations
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January 2002 in “Journal of drug targeting” Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.
81 citations
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October 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” Certain genes control the color of human hair by affecting pigment production.
81 citations
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January 2006 in “Journal of cellular physiology” Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.
81 citations
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September 2005 in “The American journal of pathology” Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.
81 citations
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February 1997 in “Journal of Investigative Dermatology” Minoxidil boosts hair growth by activating PGHS-1.
79 citations
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January 1982 in “The American Journal of Medicine” Etoposide is effective in treating several cancers, especially small cell lung cancer, with acceptable side effects.
78 citations
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February 2004 in “British Journal of Dermatology” Melatonin helps hair growth in women with hair loss.
77 citations
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January 2015 in “International Journal of Biological Macromolecules” Chitosan nanoparticles improve minoxidil delivery to hair follicles for better alopecia treatment.
77 citations
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April 2004 in “Gene expression patterns” The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.
76 citations
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July 2019 in “Scientific Reports” Baicalin nanocapsules greatly enhance its anticancer effects on breast cancer cells.
76 citations
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January 2019 in “Nanoscale” Created material boosts hair growth and kills bacteria for wound healing.
76 citations
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June 2018 in “EMBO Reports” YAP and TAZ proteins are necessary for the development of two types of skin cancer.
76 citations
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February 2015 in “Industrial Crops and Products” Researchers found over 40 compounds in Bituminaria bituminosa, including many flavonoids and some with potential for medical and hair care uses.
76 citations
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May 2011 in “Cell death and differentiation” A20 protein is crucial for normal skin and hair development.
76 citations
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March 2005 in “Journal of Molecular Medicine” Certain mice without specific receptors or mast cells don't lose hair from stress.
75 citations
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June 2019 in “International Journal of Molecular Sciences” Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.
75 citations
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November 2016 in “Medicines” Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.
75 citations
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October 2002 in “Journal of Dermatological Science” Sophora flavescens extract may help hair grow by affecting growth factors and blocking a hair-related enzyme.
75 citations
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November 1996 in “Fertility and Sterility” Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.
73 citations
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July 2016 in “Cosmetics” Mushrooms have beneficial properties for skin and hair care products and have great potential for future cosmetic use.
73 citations
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June 2010 in “PLoS Genetics” A gene mutation in mice causes hair loss, weak bones, and protein buildup, showing how protein processing issues can lead to diseases.
72 citations
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December 2012 in “Expert Opinion on Drug Delivery” Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.
72 citations
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February 2011 in “American Journal of Biological Anthropology” The conclusion is that recognizing hair growth cycles can improve the precision of dietary and health assessments from hair analysis.
71 citations
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January 2014 in “Journal of Proteome Research” Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.
70 citations
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February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
69 citations
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December 2015 in “Journal of Controlled Release” Nanocapsules can improve clobetasol delivery to hair follicles, reducing side effects.
69 citations
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December 2011 in “Journal of Ethnopharmacology” Some Thai plants, especially Carthamus tinctorius, could help prevent hair loss and promote hair growth without adverse effects.
69 citations
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September 2006 in “Human Reproduction” Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
68 citations
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March 2008 in “Experimental dermatology” The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.