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A very low-calorie ketogenic diet led to weight loss and improved metabolic and hormonal health in obese men, with better sperm motility.

Gut bacteria can lower androgen levels in male mice.

Mycophenolate mofetil is safer and more effective than cyclophosphamide for treating lupus nephritis.

The 1298CC genotype in RA patients leads to higher methotrexate toxicity, while the 1298AA genotype results in better treatment response.

The study developed a successful mouse model to study skin infections, highlighting the importance of choosing the right fungal strains.

Methotrexate is not proven effective for inducing remission in ulcerative colitis.

17α-estradiol extends lifespan and improves metabolism in male mice through the estrogen receptor α.

Low-dose methotrexate effectively regrows hair in many alopecia areata patients but can cause some side effects.

Losing Memo protein shortens lifespan and affects health.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

A horse in Brazil with skin and gut issues was diagnosed with a severe disease and had to be euthanized.

Deleting the Sox21 gene changes hair lipid composition and increases cholesterol sulfate levels.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

The wolves suspected of man-eating in the 1880s likely ate very little human flesh and mostly consumed a diet similar to herbivores and omnivores.

Sex steroids affect the MafB gene differently in male and female hamsters.

Biotin mega-dose therapy led to dramatic improvement in a newborn with a rare metabolic disorder.

Melatonin given to pregnant rabbits improved their babies' fur quality.

Glutamine helps macrophages reduce inflammation and improve wound healing.

Pegvaliase effectively reduces blood phenylalanine levels in most PKU patients, but requires personalized plans and good communication to manage side effects.

Suppressing ODC activity reduces tumor growth in hair follicles.

Lack of sleep in mice leads to prostatitis by reducing certain hormones and activating an inflammatory pathway, which can be temporarily fixed with normal sleep.

A specific genetic mutation causes POMC deficiency, leading to symptoms like weight gain and red hair.

Biotin should be added to Japanese amino acid formula to prevent deficiency.

Diet and sunlight are important for maintaining good vitamin D levels.

Urinary and serum selenium levels are the best indicators of selenium intake in dogs.

A 6-year-old boy with autism improved his thyroid function and growth after addressing iodine deficiency caused by picky eating, but his psychiatric symptoms and picky eating continued.

Urinary Se to creatinine ratio, serum Se, and glutathione peroxidase are effective early biomarkers for selenium status in dogs.

Loss of Dnmt3a and Dnmt3b leads to more aggressive skin tumors, but blocking PPAR-γ can reduce this effect.