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A new syndrome was linked to two new genetic changes in the MBTPS1 gene in a 14-year-old girl.

Using tacalcitol ointment with photodynamic therapy may effectively treat follicular mucinosis with scalp hair loss.

A new method was developed to measure and assess the activity and inhibition of the enzyme steroid 5α-reductase.

Methotrexate is a promising and safe treatment for severe alopecia areata, with better results when combined with corticosteroids.

The method effectively measures drug impact on DHT levels in prostate treatments.

5α-reductase 2 is crucial for stress response in male rats.

Monitor methotrexate side effects, research cannabis treatments, and use mycophenolate mofetil for lupus nephritis.

The NUDT15 gene variant causes severe side effects from azathioprine in some Indian patients.

Blocking mTORC1 activity could increase hair pigmentation and potentially reverse greying.

Smoking reduces antioxidants and causes DNA damage in hair follicles.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Mutations in the hHb6 gene cause the hair disorder monilethrix.

Tretinoin boosts minoxidil's effect on hair loss by increasing enzyme activity.

Maternal melatonin improves offspring hair growth by affecting specific proteins and pathways.

A new mutation in the KRT86 gene causes monilethrix in a Han family.

Methotrexate effectively treated a 2-year-old's generalized pustular psoriasis without side effects.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

A mutation in the VDR gene affects hair cycling without needing ligand binding.

Progesterone affects GABA_A receptor function by altering δ subunit levels.

Hibiscus rosa sinensis may help manage hair loss.

Long-term use of minoxidil may cause hair follicles to transform into noticeable terminal hairs, leading to trichostasis spinulosa.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

Minoxidil activates hair growth by being sulfated by P-PST in the human liver.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

A new gene mutation causes hereditary coproporphyria with reduced enzyme activity.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

The development of breeding tubercles in male zebrafish relies on a specific enzyme that processes hormones.

The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.