research Anais do V International Workshop on Rational Use of Medicines.
The workshop promoted better medicine use and health practices through global collaboration.
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research Chemically Induced Hair Loss/Alopecia
Some chemicals and drugs can cause hair loss, which usually grows back after stopping the treatment.
research Efectos de la alteración de los niveles de allopregnanolona durante periodos críticos del neurodesarrollo en la vulnerabilidad al consumo de alcohol
Early NAS level changes affect alcohol consumption vulnerability.
research Poster Abstracts
The model and estimator can predict drug exposure in kidney transplant patients well.
research Table of Contents
Second-generation antipsychotics offer no significant benefit over first-generation ones for schizophrenia.
research P.6.028 Transnosography of impulsiveness:A comparison among different psychiatric disorders
Impulsiveness is common across various psychiatric disorders and linked to many psychological symptoms.
research High resolution full scan liquid chromatography mass spectrometry comprehensive screening in sports antidoping urine analysis
The method effectively detects banned substances in urine for sports antidoping.
research New lifestyle drugs and somatoform disorders in dermatology
The article concludes that dermatologists should prescribe lifestyle drugs carefully and consider mental health treatments for patients with disorders like BDD.
research 3a-Phenylhexahydropentalene-1,6-dione
A rigid compound with a common structural motif was successfully synthesized.
research A COMPREHENSIVE REVIEW ON PHARMACOLOGICAL POTENTIALS OF CAFFEINE
Caffeine boosts alertness, helps breathing, acts as a diuretic, and may aid cancer treatment.
research Role of Phenylalanine and Its Metabolites in Health and Neurological Disorders
Phenylalanine may help with depression but can cause issues if not properly processed.
research Attenzione divisa nei pazienti con cerebrolesione acquisita
Finasteride may cause sexual and psychological side effects by affecting an enzyme related to epinephrine.
research Diphenyl cresyl phosphate [MAK Value Documentations, 2003]
Diphenyl cresyl phosphate has low toxicity but can harm the liver, kidneys, adrenal glands, and testicles at high doses.
research Novel 5α-Reductase Inhibitors: Synthesis, Structure−Activity Studies, and Pharmacokinetic Profile of Phenoxybenzoylphenyl Acetic Acids
A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.
research Finasteride inhibits epinephrine synthesis in humans: implication for sexual dysfunction
Finasteride may cause sexual dysfunction by reducing epinephrine levels.
research Topiramate for Co-Occurring Bipolar Disorder and Disruptive Behavior Disorders
Topiramate may help improve disruptive behaviors in children with bipolar disorder.
research Minoxidil prevents 3,4-methylenedioxymethamphetamine-induced serotonin depletions: role of mitochondrial ATP-sensitive potassium channels, Akt and ERK
Minoxidil prevents serotonin loss from MDMA by affecting potassium channels and increasing Akt phosphorylation.
research Use of pegvaliase in the management of phenylketonuria: Case series of early experience in US clinics
Pegvaliase effectively reduces blood phenylalanine levels in most PKU patients, but requires personalized plans and good communication to manage side effects.
research Inhibition of 5α-reductase attenuates behavioral effects of D1-, but not D2-like receptor agonists in C57BL/6 mice
Finasteride reduces certain behaviors caused by D1-like receptor agonists but not by D2-like receptor agonists in mice.
research Megestrol Acetate Increases the Proliferation, Migration, and Adipogenic Differentiation of Adipose-Derived Stem Cells via Glucocorticoid Receptor
Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.
research New Synthesis of Methyl 3β-Hydroxy-5-androstene-17β-carboxylate
A new method was developed to make a compound used in finasteride and epristeride with a 69% yield.
research Reversal of caffeine-induced anxiety by neurosteroid 3-alpha-hydroxy-5-alpha-pregnane-20-one in rats
A neurosteroid can reduce caffeine-induced anxiety in rats.
research Methotrexate in the treatment of steroid-dependent asthma
Methotrexate reduced the need for steroids in asthma patients without worsening their condition.
research A Transition State Analogue of 5′-Methylthioadenosine Phosphorylase Induces Apoptosis in Head and Neck Cancers
MT-DADMe-ImmA can selectively kill head and neck cancer cells without harming normal cells.
research METYRAPONE AS A BRIDGING THERAPY IN FLORID CUSHING’S DISEASE PATIENT PRIOR TO PITUITARY ADENOMECTOMY
Metyrapone effectively stabilizes severe Cushing's disease symptoms before surgery.
research Advancing mitochondrial therapeutics: Synthesis and pharmacological evaluation of pyrazole-based inhibitors targeting the mitochondrial pyruvate carrier
New pyrazole-based inhibitors show promise for treating metabolic diseases and other conditions.
research Midazolam Ameliorates the Behavior Deficits of a Rat Posttraumatic Stress Disorder Model through Dual 18 kDa Translocator Protein and Central Benzodiazepine Receptor and Neurosteroidogenesis
Midazolam reduces PTSD-like behavior in rats by acting on specific brain receptors.
research The effects of methylated flavonoids on depression-like activity and pro-inflammatory cytokine thresholds in mice induced by repeated finasteride administration
Methylated flavonoids may effectively reduce depression and inflammation caused by finasteride.
research P-50 WE KNOW YOU ARE THERE: MISSING MASS
Metyrapone can effectively treat Cushing's Disease even if the mass causing it is not found.
research Cloning of the human phenol sulfotransferase gene family: three genes implicated in the metabolism of catecholamines, thyroid hormones and drugs
Scientists identified three genes important for processing certain brain chemicals, thyroid hormones, and medications.