research Metabolic Syndrome, Hepatic Steatosis and Testosterone: A Matter of Sex
Sex hormones affect liver fat and metabolic health differently in men and women.
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420-450 / 1000+ resultsresearch Lupus erythematosus tumidus (LET) with autoimmune thyroid dysfunction (AITD) as the first presentation of systemic lupus erythematosus: A case report and review of the literature
Recognizing LET and AITD can help diagnose SLE early for better treatment.
research Stem cell and extracellular matrix-related molecules increase following melatonin treatment in the skin of postmenopausal rats
Melatonin treatment helps improve skin health in postmenopausal rats.
research Altered Hormone and Bioactive Lipid Plasma Profile in Rodent Models of Polycystic Ovarian Syndrome Revealed by Targeted Mass Spectrometry
Rodent models of PCOS show some hormone changes similar to humans, but also have key differences.
research Neurosteroids on the Epilepsy Chessboard—Keeping Seizures in Check
Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.
research Η επίδραση της απώλειας βάρους στα επίπεδα της αντιμυλλεριανής ορμόνης σε υπέρβαρες και παχύσαρκες γυναίκες με το σύνδρομο των πολυκυστικών ωοθηκών
Weight loss can lower AMH levels in overweight and obese women with PCOS.
research Glucocorticoid Receptor Antagonism Improves Glucose Metabolism in a Mouse Model of Polycystic Ovary Syndrome
Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.
research Neuropilin 2 expression and function in melanocytes and melanoma
Neuropilin 2 may be a biomarker for melanoma and affects melanocyte behavior.
research 265 Modulation of disease-central cytokine pathways with TAK-279, a highly selective oral tyrosine kinase 2 (TYK2) inhibitor, defines clinical response in patients with psoriasis
TAK-279 effectively reduces psoriasis symptoms and is safe.
research 5α-reduction of epitestosterone is catalysed by human SRD5A1 and SRD5A2 and increases androgen receptor transactivation
5α-reductases increase epitestosterone's effect on androgen receptors.
research Monilethrix with Acitretin
Acitretin improved monilethrix symptoms temporarily, but they returned after stopping treatment.
research SAT-LB82 Myxedema as Presenting Feature of Profound Primary Hypothyroidism in a Toddler
A toddler with unusual hypothyroidism symptoms improved with levothyroxine treatment.
research Functionally enhanced placenta-derived mesenchymal stem cells inhibit adipogenesis in orbital fibroblasts with Graves’ ophthalmopathy
Enhanced stem cells from the placenta can reduce fat buildup in eye tissue for Graves' disease.
research Inhibiting Biosynthesis and/or Metabolism of Progestins in the Ventral Tegmental Area Attenuates Lordosis of Rats in Behavioural Oestrus
Blocking certain brain processes reduces mating behavior in female rats.
research Improvement of Recalcitrant Folliculitis Decalvans With Tirzepatide: A Case Report
Tirzepatide improved symptoms and hair regrowth in a man with folliculitis decalvans.
research Determination of Exemestane in Human Plasma by LC-MS-MS
The method effectively showed that the two exemestane preparations are bioequivalent.
research Clinical-Exome Sequencing Unveils the Genetic Landscape of Polycystic Ovarian Syndrome (PCOS) Focusing on Lean and Obese Phenotypes: Implications for Cost-Effective Diagnosis and Personalized Treatment
Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.
research A Neutralizing Prolactin Receptor Antibody Whose In Vivo Application Mimics the Phenotype of Female Prolactin Receptor-Deficient Mice
The antibody 005-C04 blocks prolactin receptors, causing reversible infertility, impaired lactation, and hair regrowth in female mice.
research Agouti and Agouti-related Protein: Analogies and Contrasts
Agouti and AGRP affect pigmentation and obesity, with implications for metabolic disorders.
research Time-Tracking-based Research of Drug Development in Pharmaceutical Fields ——A Case Study on Metformin
The conclusion is that metformin may be useful for treating various conditions beyond diabetes and that time-tracking analysis is a good way to review drug research.
research 696 MEK and BRAF inhibitors augment the production and accumulation of sebum in hamster sebocytes
MEK and BRAF inhibitors increase sebum production and accumulation, which could cause acne-like side effects.
research Glibenclamide reverses cromakalim-induced anti-ischemic effect in conscious rabbits
research 267 Single- and multiple-ascending dose studies of DS-2325a, a KLK5 inhibitor for the treatment of Netherton syndrome
DS-2325a is safe and well-tolerated, supporting further development for Netherton Syndrome treatment.
research Management of adolescent polycystic ovary syndrome
SPIOMET therapy may be a promising alternative to oral contraceptives for treating adolescent PCOS.
research Clinical aspects of the metabolic syndrome
Losing weight and eating better are key to managing metabolic syndrome and its related conditions.
research Prolactin as a candidate sebotrop(h)ic hormone?
Prolactin may influence skin glands and could be a target for treating acne and skin aging.
research Nelfb promotes dermal white adipose tissue formation through RNA Polymerase II mediated adipogenic gene regulation
Nelfb is crucial for forming skin fat tissue by regulating genes needed for fat cell development.
research Potential of polar lipids from bovine milk to regulate the rodent dorsal hair cycle
Bovine milk fats applied to mouse skin can promote hair growth similar to known hair growth treatments.
research FREQUENCY OF METABOLIC SYNDROME IN PATIENTS WITH FEMALE PATTERN HAIR LOSS
Many women with female pattern hair loss also have metabolic syndrome.
research Serum vascular endothelial growth factor B is elevated in women with polycystic ovary syndrome and can be decreased with metformin treatment
Women with PCOS have higher levels of a certain growth factor, which can be reduced by taking metformin.