66 citations
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October 1999 in “Annals of the New York Academy of Sciences” The Skin POMC System affects hair growth and skin responses to stress.
January 2007 in “Elsevier eBooks” Alopecia areata is a reversible, autoimmune-related hair loss that can have significant emotional impact and uncertain treatment effectiveness.
January 2002 in “Proceedings of The Japanese Society of Animal Models for Human Diseases” Keratin2-6g is crucial for hair follicle development, with mutations causing cell degeneration and vacuolation.
4 citations
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July 2013 in “Journal of Dermatological Science” Pregnancy right after giving birth in mice lacking IL-10 causes milk that leads to liver issues and hair loss in their babies.
January 2017 in “Jikken doubutsu ihou/Jikken doubutsu/Experimental animals/Jikken Dobutsu” Mice with a changed Hr gene lose and regrow hair due to changes in the gene's activity.
28 citations
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November 2013 in “The FASEB journal” Mice with CBS deficiency are healthier on a low-methionine diet.
17 citations
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October 2015 in “Medicine and Pharmacy Reports” Animal models are crucial for learning about hair loss and finding treatments.
1 citations
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March 2021 in “Skin health and disease” Better hair loss models needed for research.
218 citations
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October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.
75 citations
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March 2014 in “Journal of Investigative Dermatology” Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.