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February 2017 in “Aging” SkQ1 antioxidant improved health and lifespan in mice.
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June 2018 in “Cell death and disease” Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.
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June 2001 in “Endocrinology” Prolactin affects when mice shed and grow hair.
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April 1999 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Vitamin D receptor is crucial for bone health and mineral metabolism.
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October 2002 in “Human molecular genetics online/Human molecular genetics” A gene mutation in mice causes skin defects and early death.
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January 2015 in “BioMed Research International” Certain growth factors can promote hair growth in mice by activating hair growth-related proteins.
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January 1995 in “Cells Tissues Organs” Merkel cells develop independently of nerves and are linked to specific hair follicles in mice.
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December 1966 in “Endocrinology” Injecting α-MSH made mice's hair turn black.
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April 2014 in “Radiation Research” RTA 408 cream protects mice from radiation skin damage.
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October 2010 in “Molecular Imaging and Biology” Increased skin pigmentation in mice reduces bioluminescent signal accuracy.
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July 2015 in “Journal of Immunology” Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.
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February 2016 in “Scientific reports” Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
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June 2003 in “American Journal of Physiology-cell Physiology” Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.
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July 2000 in “Toxicology Letters” K6/ODC transgenic mice are effective for quickly identifying cancer-causing chemicals.
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November 2010 in “Development” Hair follicles in mutant mice self-organize into ordered patterns within a week.
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May 2001 in “Journal of Investigative Dermatology” Excessive putrescine causes hair loss in transgenic mice by disrupting hair follicle development.
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March 2014 in “Growth Hormone & IGF Research” IGF-1 injections help mice grow more hair by increasing cell growth and blocking a hair growth inhibitor.
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November 2006 in “Journal of Endocrinology” Prolactin slows down hair growth in mice.
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May 2011 in “Phytotherapy Research” Ginseng, especially red ginseng, may help regrow hair and block a hair loss-related enzyme.
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November 1984 in “Journal of Heredity” Lethal-milk mice produce zinc-deficient milk, causing health issues in pups unless supplemented with zinc.
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September 2016 in “Genes Brain & Behavior” Zfp462 deficiency in mice causes anxiety-like behaviors and excessive self-grooming.
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April 2006 in “Journal of Investigative Dermatology” TRPV1 helps regulate hair growth cycles.
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Disrupting Acvr1b in mice causes severe hair loss and thicker skin.
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December 2016 in “Cell Death & Differentiation” Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.
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September 2011 in “Journal of Ethnopharmacology” Panax ginseng extract helps mice grow hair.
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November 2021 in “npj Regenerative Medicine” Adult spiny mice recover better from heart attacks than common lab mice.
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July 2015 in “Kidney International” IL-3 worsens lupus nephritis and blocking it improves kidney health.
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November 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Fatp4 is crucial for healthy skin development and function.
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September 1997 in “The journal of investigative dermatology/Journal of investigative dermatology” A mutation in mice causes hair loss and skin issues due to a defect in a gene affecting cell adhesion.
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January 2010 in “Journal of Clinical Investigation” N-WASP is essential for normal hair growth in mice.