January 2006 in “Zhongguo yaoke daxue xuebao” The method accurately measures vinflunine in dog plasma.
24 citations
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June 2018 in “Expert Review of Pharmacoeconomics & Outcomes Research” Microneedle technology is beneficial for drug delivery and could make vaccinations cheaper and more accessible.
90 citations
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November 1980 in “Annals of Internal Medicine” Long-term use of minoxidil for high blood pressure can delay kidney failure in some patients and improve kidney function in others with severe hypertension.
The tool accurately measures hair count and size on scalps with 79.45% and 68.19% accuracy, respectively.
68 citations
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August 2012 in “Journal of the American Academy of Dermatology” Dermatoscopy is a useful tool for diagnosing hair disorders and can help choose samples for more detailed analysis.
7 citations
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April 2025 in “Science Advances” This study explores a novel silicate-based therapy for inflammatory dilated cardiomyopathy (iDCM), a severe condition resulting from myocarditis. Researchers developed composite microneedles and ion solutions using calcium silicate bioceramics to deliver SiO3 2− ions directly to myocardial tissue or through systemic circulation. These ions modulate the cell microenvironment by regulating CD4 + T/T helper 17 (T H 17) cells and their interactions with neutrophils and fibroblasts via the FOXO signaling pathway. The therapy inhibits the hyperdifferentiation of CD4 + T cells to T H 17 cells and the transformation of neutrophils and fibroblasts, disrupting the cycle of inflammation and fibrotic lesions in iDCM. This biomaterial-based strategy shows promise for treating iDCM.
14 citations
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August 2018 in “Journal of Pharmaceutical and Biomedical Analysis”
4 citations
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October 1988 in “Clinics in Dermatology” Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.
December 2012 in “http://isrctn.org/>” 26 citations
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July 2023 in “International Journal of Nanomedicine” The microneedle system shows promise for non-invasive brain drug delivery.