52 citations
,
March 2015 in “Tissue Engineering Part C Methods” 3D images of skin show collagen is evenly spread, but elastic fibers are fewer near hair follicles.
18 citations
,
June 1993 in “Archives of Dermatological Research” Human hair follicles can be used to create skin-like tissue for wound healing and drug testing.
July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists created a new 3D skin model from cells of plucked hairs that works like real skin and is easier to get.
110 citations
,
August 2011 in “Journal of Visualized Experiments” 3D skin models better mimic human skin and melanoma progression than older methods.
March 2007 in “Journal of Plastic Reconstructive & Aesthetic Surgery” A new method was developed to create better skin models for healing and reconstruction.
August 1993 in “Journal of Dermatological Science”
17 citations
,
January 1997 in “Cell and Tissue Research” Scientists developed a method to grow human fetal skin and digits in a lab for 3-4 weeks, which could help study skin features and understand genetic interactions in tissue formation.
48 citations
,
August 2001 in “Experimental dermatology” Researchers created a quick, cost-effective way to make skin-like tissue from hair follicles and fibroblasts.
1 citations
,
February 2017 in “International journal of anatomy and research” Understanding fetal skin development helps diagnose congenital skin diseases.
January 2025 in “Online Publication Service of Würzburg University (Würzburg University)” A protocol was developed to create 3D skin models from adult diseased cells to study Small Fiber Neuropathy.
13 citations
,
January 2001 in “Skin pharmacology and physiology” Micro-Imager® helps see how drugs spread in human skin.
A skin model using hair and skin cells can mimic human skin for research.
13 citations
,
April 2016 in “Journal of Visualized Experiments” The method successfully isolates hair follicle stem cells and skin cells from mice for research.
2 citations
,
January 1989 Researchers developed a method to grow skin-like tissue from hair cells.
12 citations
,
May 2016 in “Experimental Dermatology” A new skin model from hair follicles is a safer, simpler alternative for skin tests.
69 citations
,
June 2017 in “Experimental Biology and Medicine” Advanced human skin models improve drug development and could replace animal testing.
221 citations
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June 1999 in “In Vitro Cellular & Developmental Biology - Animal”
4 citations
,
May 2013 in “Dermatologic Surgery” Three new techniques simplify and improve the preparation of tissue samples for skin cancer surgery.
88 citations
,
April 1981 in “Molecular and cellular biochemistry” December 2025 in “Advanced Healthcare Materials” The Spherical Skin Model improves drug and cosmetic testing by accurately mimicking human skin for efficient compound screening.
September 2019 in “Journal of Investigative Dermatology” Researchers developed a 3D skin model with its own immune and blood vessel cells to better understand skin health and disease.
5 citations
,
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Aging skin shows thinner layers, fewer hair follicles, and new biomarkers like increased space between cells and smaller sebaceous glands.
August 2019 in “Journal of Investigative Dermatology” The study found that tight junctions reach the top layer of the skin's stratum granulosum, not just the second top layer as previously thought.
2 citations
,
June 2020 in “Journal of Investigative Dermatology” 3D imaging of skin biopsies offers better accuracy but is time-consuming and can't clear melanin.
2 citations
,
May 2025 in “Advanced Science” Microspheric skin organoids can be used for drug testing, identifying Minoxidil as a Wnt pathway activator.
10 citations
,
August 2023 in “Developmental cell” The research maps the complex development of early mouse skin, identifying diverse cell types and their roles in forming skin layers and structures.
August 2024 in “STAR Protocols” The document provides a detailed method for analyzing gene expression in skin samples with hair follicles.
January 2026 in “Microsystems & Nanoengineering” New technologies replicate human skin for testing without animals.
31 citations
,
January 2021 in “Experimental Dermatology” Skin organoids are a promising new model for studying human skin development and testing treatments.
3 citations
,
December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.