April 2009 in “Journal of Pain” Finasteride reduces pain in male rats and works better with testosterone.
26 citations
,
September 2005 in “Pharmacology Biochemistry and Behavior” 5alpha-reductase 2 is crucial for proper male brain development and sexual differentiation.
215 citations
,
November 2006 in “Journal of The American Academy of Dermatology” Dutasteride more effective for hair growth, but has more side effects than finasteride.
21 citations
,
October 2015 in “Current Drug Targets” Both dutasteride and finasteride improve urinary symptoms, but dutasteride may be better at reducing the risk of prostate surgery and sudden inability to urinate.
May 2026 in “International Journal of Scientific Research in Chemistry” Finasteride breaks down into new compounds under acidic conditions.
3 citations
,
April 2019 in “Human & Experimental Toxicology” Finasteride causes harmful organ changes in female mice.
January 2026 in “Rinsho Shinkeigaku” Finasteride and minoxidil may increase stroke risk by affecting blood clotting and blood pressure.
1 citations
,
February 2022 in “Brain Research Bulletin” Finasteride may help reduce impulsivity caused by pramipexole.
June 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” Combining finasteride with dimethyl-β-cyclodextrin improves its absorption and bioavailability.
February 2017 in “대한피부과학회지” Combining low-dose dutasteride with finasteride improved a man's hair loss.
September 2023 in “The Journal of Steroid Biochemistry and Molecular Biology” Stopping finasteride for male pattern hair loss changes neuroactive steroid levels in the brain and blood.
9 citations
,
August 2000 in “Journal of Periodontal Research” Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.
72 citations
,
April 2008 in “The Journal of urology/The journal of urology” Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.
66 citations
,
June 2006 in “Journal of The American Academy of Dermatology” Finasteride increases hair weight and count in men with hair loss, with best results after four years.
1 citations
,
February 2008 in “Nature Clinical Practice Urology” Finasteride's sexual side effects may be due to nocebo effect.
63 citations
,
December 2013 in “PLoS ONE” Finasteride may reduce prostate cancer spread by lowering certain enzyme levels.
June 2026 in “Pharmaceuticals” 5α-Reductase inhibitors, like finasteride, can cause serious, persistent side effects not always listed in official drug information.
November 2003 in “Journal of Dermatology” Finasteride's link to depression is questionable due to study flaws and potential bias.
8 citations
,
February 2014 in “General and Comparative Endocrinology” Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.
15 citations
,
March 1997 in “International Journal of Dermatology” Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.
January 2011 in “Reactions Weekly”
7 citations
,
April 2015 in “JAMA Dermatology” Finasteride's potential harms are hard to accurately measure.
September 2021 in “Fertility and Sterility” Public interest in finasteride's sexual side effects has significantly increased, highlighting the need for better patient discussions.
5 citations
,
February 2013 in “Journal of Liquid Chromatography & Related Technologies” Method accurately measures finasteride concentration in medicine.
9 citations
,
October 2017 in “Molecular Medicine Reports” Finasteride causes reduced tear flow and severe eye inflammation.
23 citations
,
January 2002 in “Journal of Cutaneous Medicine and Surgery” Finasteride helps hair growth by decreasing cell death in hair follicles.
January 2016 in “Reactions Weekly” No clear link found between finasteride and suicidal thoughts or actions.
2 citations
,
March 2020 in “Baghdad Science Journal” Finasteride effectively reduces DHT and E2 levels, helping with prostate enlargement.
Sublingual minoxidil increases hair thickness in men with hair loss.