research A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity
Keratin is crucial for skin barrier formation and affects mitochondrial function.
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510-540 / 1000+ resultsresearch The Relationship Between Glycine and Gephyrin in Synapses of the Rat Spinal Cord
Glycine is a key transmitter in rat spinal cord synapses, often alongside GABA.
research Genes for intermediate filament proteins and the draft sequence of the human genome
The study found 65 intermediate filament genes, including new keratins, and suggested updating keratin naming.
research Pan-tissue scaling of stiffness versus fibrillar collagen reflects contractility-driven strain that inhibits fibril degradation
Tissue stiffness is influenced by contractility, which suppresses collagen breakdown.
research Human Scalp Dermal Papilla and Fibrous Sheath Cells have a different expression profile of Matrix Metalloproteinases in vitro when compared to Scalp Dermal Fibroblasts
Scalp dermal papilla and fibrous sheath cells have different MMP expression than scalp dermal fibroblasts.
research From a stem-cell–centered to a niche-centered view: the core role of collagen networks in hair loss and hair follicle miniaturization
Collagen networks play a key role in hair loss and follicle miniaturization.
research Hair Follicles as Micro-Organs: MicroRNA-Mediated Control of Growth, Cycling, and Fiber Traits
MicroRNAs play a key role in controlling hair growth and quality in sheep and goats.
research The Fate of Trichohyalin
Trichohyalin is modified by enzymes to form strong structures in hair cells.
research Expression of an Olfactomedin-Related Gene in Rat Hair Follicular Papilla Cells
FP-1 is a key protein in rat hair growth, active only during the growth phase.
research Mutations in the helix termination motif of mouse type I IRS keratin genes impair the assembly of keratin intermediate filament
Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.
research Epidermal and hair follicle trans glutaminases and crosslinking in skin
research 09-P003 Leucine rich repeat transmembrane proteins Nlrr1 and Flrt3 and early embryonic myogenesis
research Micropatterned composite membrane guides oriented cell growth and vascularization for accelerating wound healing
Micropatterned membranes speed up wound healing by guiding cell growth and blood vessel formation.
research LB1081 Three-dimensional imaging of tight junction-network across multiple layers of human epidermis by array tomography using backscattered electron-mode scanning electron microscopy
The study found that tight junctions reach the top layer of the skin's stratum granulosum, not just the second top layer as previously thought.
research Ultrastructural visualization of cross-linked protein features in epidermal appendages
Cross-linked proteins help maintain the structure of hair, feathers, and hagfish teeth.
research Endothelin-1 combined with extracellular matrix proteins promotes the adhesion and chemotaxis of amelanotic melanocytes from human hair follicles in vitro
Endothelin-1 helps amelanotic melanocytes stick and move better on certain proteins.
research Micro-Mechanical Fractional Skin Rejuvenation
The new device safely and effectively rejuvenates skin, making it thicker and healthier.
research Transcriptome analysis of frontal fibrosis alopecia revealed involvement of immune cells and ferroptosis
The research suggests that immune cells and a specific type of cell death called ferroptosis are involved in Frontal fibrosis alopecia.
research Dynamics of Merkel Cell Patterns in Developing Hair Follicles in the Dorsal Skin of Mice, Demonstrated by a Monoclonal Antibody to Mouse Keratin 8
Merkel cells develop independently of nerves and are linked to specific hair follicles in mice.
research Dermal fibrosis in male pattern hair loss: a suggestive implication of mast cells
Mast cells might contribute to hair loss by causing skin thickening.
research Pili Annulati with Multiple Fragile Hairs
Frequent hairdryer use may worsen hair fragility in people with Pili Annulati.
research Comparative proteomic analyses using iTRAQ-labeling provides insights into fiber diversity in sheep and goats
The research found specific proteins that affect fiber characteristics and hair growth in sheep and goats.
research Keratin intermediate filaments in the colon: guardians of epithelial homeostasis
Keratin proteins are essential for keeping the cells in the human colon healthy and stable.
research Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Existing in Direct Proximity with the Distal End of the Arrector Pili Muscle
Certain skin cells near the base of hair muscles may help renew and stabilize skin, possibly affecting skin disorder understanding.
research Outer root sheath (ORS) cells organize into epidermoid cyst-like spheroids when cultured inside Matrigel: a light-microscopic and immunohistological comparison between human ORS cells and interfollicular keratinocytes
research Filaggrin mutations as an archetype for understanding the pathophysiology of atopic dermatitis
Filaggrin mutations are linked to atopic dermatitis and help explain how genetics and environment affect the disease.
research Ex vivo SIM-AFM measurements reveal the spatial correlation of stiffness and molecular distributions in 3D living tissue
Collagen makes skin stiff, and preservation methods greatly increase tissue stiffness.
research [A three-dimensional observation of human hair tissue treated by modified trypsin-HC1 method].
The method allows detailed observation of hair tissue structures.
research MiR-23b and miR-133 cotarget TGFβ2/NOTCH1 in dermal fibroblasts and affect hair follicle development in sheep
Two microRNAs affect hair follicle development in sheep by targeting specific genes.
research Hair Shaft Morphology, Elemental Composition, and Nanoparticles in Frontal Fibrosing Alopecia: A Case-control Study
Titanium nanoparticles may trigger frontal fibrosing alopecia, so avoid products with them.