Finasteride significantly reduced sperm production and caused testicular atrophy in hamsters.
January 1987 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Norethisterone (jenapharm) therapy is effective for endometrial cancer.
16 citations
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August 2014 in “International Journal of Women's Health” The estradiol valerate/dienogest oral contraceptive helps with heavy periods, may improve acne and symptoms in PCOS, and doesn't affect sexual function.
19 citations
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March 1987 in “International Journal of Dermatology” A drug called cimetidine can help treat hair loss in women by blocking androgen receptors. However, it's not the first choice and needs more research.
July 2020 in “CRS 2020 Virtual Annual Meeting” Researchers developed a new skin patch that delivers more finasteride into the skin, potentially improving treatment for hair loss and prostate issues.
269 citations
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May 2002 in “Hormones and Behavior” Lowering 3α,5α-THP in the hippocampus increases anxiety and depression in proestrous rats.
5alpha-DHP may be a safe, effective treatment for certain seizures without causing sedation.
6 citations
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March 2018 in “Journal of Chromatography A” New method accurately measures finasteride and M3 in urine, helping evaluate pharmacokinetics.
7 citations
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August 2019 in “Journal of Ovarian Research” Blood removal and birth control pills both helped with hormone levels in women with PCOS, but birth control was better for regular periods and blood removal had fewer side effects.
17 citations
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November 2017 in “Experimental physiology” Breathing in newborn rats is affected differently by hormones based on their sex.
75 citations
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March 1999 in “Fertility and sterility” Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.
1 citations
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January 2001 in “Endocrine Practice” Topical finasteride may help treat facial hirsutism in women.
2 citations
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June 2012 in “Digestive Diseases and Sciences” Finasteride and methadone don't increase advanced liver disease risk in HCV+ male veterans.
January 2025 in “Journal of the American Academy of Dermatology” Combining oral minoxidil and bicalutamide may help improve hair growth in adolescent girls.
1 citations
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January 2022 in “European Journal of Pharmacology” Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.
A new lipid-based formula using myristyl myristate can improve estradiol treatment for hair loss.
5 citations
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January 2021 in “Daru” A woman had severe reactions to methotrexate, including skin issues and organ problems, but improved after 38 days in the hospital.
3 citations
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April 2019 in “Human & Experimental Toxicology” Finasteride causes harmful organ changes in female mice.
50 citations
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April 2000 in “Fertility and Sterility” Diane 35 plus finasteride is more effective in reducing hair growth and androgen levels, but may decrease libido.
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December 2024 in “EClinicalMedicine” Anti-androgens are not better than birth control pills for PCOS, but can help with excess hair if pills don't work.
232 citations
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June 1975 in “Journal of Steroid Biochemistry” Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.
May 2018 in “Más dermatología” The higher dose supplement was more effective in treating female hair loss.
February 2026 in “International Journal on Science and Technology” Vitex negundo may help treat PCOD, but more human studies are needed.
10 citations
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June 2016 in “PLOS ONE” Finasteride boosts immune cells that suppress T-cells, possibly helping with immune disorders but may increase cancer risk.
Different medications improved various PCOS symptoms and quality of life in Pakistani women, but did not significantly help with excessive hair growth.
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November 1990 in “DICP”
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February 1989 in “Fertility and sterility” Cimetidine did not reduce hair growth in women with hirsutism.
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October 2001 in “Analytical Sciences” A new compound that could treat various androgen-related conditions was created and analyzed.
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April 2021 in “Journal of Medicinal Chemistry” Finasteride may affect PNMT, causing side effects.
Finasteride worsens alcohol withdrawal in female mice but eases it in male mice.