research A novel actor in skin biology: the mineralocorticoid receptor
Blocking the mineralocorticoid receptor can help treat skin thinning caused by steroids.
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30 / 1000+ resultsresearch Current Therapeutic Approaches to Chronic Central Serous Chorioretinopathy
New treatments for chronic central serous chorioretinopathy show promise in preventing permanent vision loss.
research Oral medications for central serous chorioretinopathy: a literature review
Some oral medications may help treat central serous chorioretinopathy, especially eplerenone, but more research is needed.
research The Acute Anticonvulsant Effects of Deoxycorticosterone in Developing Rats: Role of Metabolites and Mineralocorticoid‐receptor Responses
Deoxycorticosterone and its metabolites help prevent seizures by interacting with specific receptors.
research The myeloid mineralocorticoid receptor regulates dermal angiogenesis and inflammation in glucocorticoid‐induced impaired wound healing
Blocking the mineralocorticoid receptor improves wound healing by reducing inflammation and promoting blood vessel growth.
research Endocrinology of Transgender Medicine
Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.
research SARS-CoV-2 Spike Protein S1-Mediated Endothelial Injury and Pro-Inflammatory State Is Amplified by Dihydrotestosterone and Prevented by Mineralocorticoid Antagonism
Spironolactone may help reduce COVID-19 severity in men by blocking harmful effects of certain hormones.
research Association between Mineralocorticoid Receptor Antagonist and Mortality in SARS-CoV-2 Patients: A Systematic Review and Meta-Analysis
Mineralocorticoid receptor antagonist therapy does not significantly reduce mortality in COVID-19 patients.
research Adrenal causes of endocrine hypertension in childhood or adolescence
Adrenal disorders often cause high blood pressure in young people.
research Androgen excess: Investigations and management
The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.
research Acne
Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.
research Hormonal therapies for acne
Hormonal treatments can improve acne, but they come with potential side effects and risks.
research Hormone therapy in acne
Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.
research Treatment of androgen excess in females: Yesterday, today and tomorrow
The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.
research Organizational Effects of Estrogens and Androgens on Estrogen and Androgen Receptor Expression in Pituitary and Adrenal Glands in Adult Male and Female Rats
Early hormones shape sex-specific differences in rat glands.
research Roles of steroid receptors in the lung and COVID-19
Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.
research Hypertension's 3 Dilemmas and 3 Solutions: Pharmacology of the Kidney in Hypertension
Re-evaluating minoxidil, reducing sodium intake, and addressing arteriolar hypertrophy can improve hypertension management.
research Case report: A pregnant woman accidental treated with spironolactone in mid-gestation
The woman delivered a healthy baby boy despite taking spironolactone during pregnancy.
research Cutaneous Androgen Metabolism: Basic Research and Clinical Perspectives
Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.
research Pharmacodynamic Evaluation: Endocrinology
The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.
research Abiraterone and spironolactone in prostate cancer: a combination to avoid
Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.
research Pharmacokinetics and Bioconversion of Dehydroepiandrosterone after Application of Dexamethasone in Women with Polycystic Ovary Syndrome
Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.
research Hypertension: sex-related differences in drug treatment, prevalence and blood pressure control in primary care
Women experience more side effects and have worse blood pressure control from hypertension treatments than men, despite using different medications.
research Lisinopril-Induced Alopecia: A Case Report
Lisinopril, a heart medication, probably caused hair loss in a patient, which stopped after switching drugs.
research TREATMENT OF REFRACTORY HYPERTENSION
Most patients with hard-to-treat high blood pressure can be managed effectively with various treatments, but no single treatment is perfect.
research Influence of spironolactone treatment on endothelial function in non-obese women with polycystic ovary syndrome
Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.
research Efficacy and safety of systemic spironolactone for acne in female patients in Sulaymaniyah teaching center of dermatology
Spironolactone is effective and safe for treating acne in women, especially those over 25 with hormonal imbalances.
research A Novel Point Mutation in the Ligand-Binding Domain (LBD) of the Human Glucocorticoid Receptor (hGR) Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus of hGR LBD in Conferring Transactivational Activity
A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.
research Hypertension and aldosterone levels in women with early-onset androgenetic alopecia
Women with early hair loss have higher blood pressure and aldosterone; screening and treatment may help.
research Repurposing existing drugs for COVID-19: an endocrinology perspective
Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.