42 citations
,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
11 citations
,
May 2009 in “Medical Hypotheses” Male pattern baldness is an unintended side effect of the body's use of androgens for muscle growth, especially in those genetically prone to it.
8 citations
,
April 2017 in “Journal of Dermatological Science” Hair loss is caused by the breakdown of a protein called COL17A1 in hair follicle stem cells.
January 2014 in “American Journal of Medicine and Medical Sciences” Minoxidil, originally a blood pressure medication, is effective in treating hair loss in men and women, with different strengths recommended for each.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Durdhuradi Taila may help promote hair growth and reduce hair loss.
June 2024 in “Computational and Structural Biotechnology Journal” Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
116 citations
,
September 2001 in “Journal of The American Academy of Dermatology” Hair loss occurs due to fewer papillary cells, smaller follicles, and shorter growth phases.
25 citations
,
September 2018 in “Scientific Reports” Morroniside may help hair grow and stay in its growth phase by affecting certain cell signals.
100 citations
,
June 2006 in “British Journal of Dermatology” Hair loss severity relates to increased miniaturization in female pattern hair loss.
212 citations
,
September 2015 in “Journal of Investigative Dermatology” The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.
211 citations
,
April 2013 in “Development” More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.
109 citations
,
December 1998 in “The Journal of Dermatology” Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.
74 citations
,
January 2013 in “Expert Opinion on Biological Therapy” The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.
66 citations
,
June 2010 in “Experimental Dermatology” The hair follicle is a great model for research to improve hair growth treatments.
27 citations
,
January 2020 in “Experimental Dermatology” Immune cells affect hair growth and could lead to new hair loss treatments.
22 citations
,
February 2002 in “Journal of theoretical biology” The model showed that randomness accurately describes individual hair growth cycles and that synchronization can cause large fluctuations not seen in humans.
8 citations
,
June 2019 in “Scientific Reports” Increased PPARGC1α relates to hair thinning in common baldness.
February 2025 in “Plastic and Aesthetic Research” Minoxidil and finasteride effectively promote hair regrowth within 3 months.
April 2017 in “Journal of Investigative Dermatology” The hair follicle dermal sheath is essential for hair shedding and needs to communicate with the outer root sheath for normal hair growth cycles.
January 2008 in “Pratique médicale & chirurgicale de l'animal de compagnie” Alopecia X in dogs is a cosmetic issue, not a hormonal disorder, and harmful treatments should be avoided.
38 citations
,
April 2016 in “Experimental Dermatology” The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.
11 citations
,
October 1994 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride increases hair growth, prolongs hair cycle, and lowers dihydrotestosterone levels.
54 citations
,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Disruptions in hair follicle fibroblast dynamics can cause hair growth problems.
54 citations
,
June 1985 in “American Journal of Dermatopathology” Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.
30 citations
,
December 2018 in “Trends in Endocrinology and Metabolism” Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.
5 citations
,
September 2016 in “Journal of Cosmetic Dermatology” Nourkrin® with Marilex® may increase hair count by 35.7% in postpartum hair loss.
4 citations
,
December 2014 in “European Journal of Chemistry” Iron chloride helps create compounds that could be useful in medicine, like treating hair loss.
3 citations
,
June 2006 in “Expert Review of Dermatology” The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.
2 citations
,
May 2001 in “Current problems in dermatology” The conclusion is that effectively treating hair disorders is difficult due to the complex factors affecting hair growth and more research is needed to improve treatments.
120 citations
,
November 2014 in “Biological Reviews” The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.