February 2025 in “Expert Opinion on Drug Safety” Topical minoxidil may cause more side effects than currently listed, needing updated safety information.
12 citations
,
February 1999 in “British Journal of Dermatology” Minoxidil increased small openings in blood vessel walls near growing hair in rats.
June 2024 in “European Journal of Pharmaceutics and Biopharmaceutics” Using photoacoustic waves to deliver minoxidil improves hair growth effectively and safely.
74 citations
,
May 2004 in “Journal of Clinical Hypertension” Minoxidil effectively treats severe hypertension, but watch for side effects.
October 2016 in “International journal of medical research and review” Minoxidil, a hair loss treatment, may cause acne-like skin eruptions.
27 citations
,
April 1992 in “Biochemical Journal” Minoxidil reduces lysine hydroxylase in skin cells.
52 citations
,
May 2019 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil effectively improves male hair loss with mild side effects.
17 citations
,
March 1985 in “Journal of The American Academy of Dermatology” Minoxidil can lower blood pressure in some people.
6 citations
,
September 1988 in “Drug intelligence & clinical pharmacy” Minoxidil caused a severe rash in a patient, which improved after stopping the drug.
March 2020 in “Hair transplant forum international” Taking minoxidil by mouth for hair growth might not be safe if you also take aspirin.
March 2024 in “Journal of the Dermatology Nurses’ Association” Low-dose oral minoxidil is being revisited as a promising hair loss treatment.
January 2017 in “Faculty of 1000 Research Ltd” Oral minoxidil significantly reduces hair shedding in women with chronic telogen effluvium.
1 citations
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October 2024 in “JACC Case Reports” Minoxidil can cause heart inflammation, so users should be monitored.
50 citations
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September 1975 in “American Heart Journal” Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.
68 citations
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September 1990 in “Biochemical Pharmacology” Minoxidil activates hair growth by being sulfated by P-PST in the human liver.
13 citations
,
February 2018 in “Bio-medical Materials and Engineering” Minoxidil inside tiny particles can deliver more drug to hair follicles, potentially improving treatment for hair loss.
34 citations
,
March 2004 in “Journal of Liposome Research” Minoxidil-loaded liposomes effectively deliver to hair follicles, potentially improving hair growth and treating alopecia.
13 citations
,
April 2009 in “Acta Medica Scandinavica” Minoxidil lowers blood pressure and causes hair growth, with some side effects.
February 2024 in “PubMed” The new minoxidil lotion using Aloplus Total is stable and can be mixed with other ingredients for treating hair loss.
September 2024 in “Journal of the American Academy of Dermatology” Media attention increased oral minoxidil prescriptions for English-preferring patients but not for Spanish-preferring patients.
January 1997 in “Fundamental & Clinical Pharmacology” August 2022 in “Journal of The American Academy of Dermatology” A 5-mg dose of oral minoxidil slightly lowers blood pressure temporarily, especially in those with higher initial blood pressure.
4 citations
,
May 2019 in “PubMed” Topical minoxidil does not change the activity of hair follicle enzymes that metabolize it.
1 citations
,
July 2025 in “International Journal of Women’s Dermatology” Women's minoxidil products cost more and are less effective than men's.
3 citations
,
May 2022 in “Journal of The American Academy of Dermatology” The conclusion is that 24 weeks of low-dose oral minoxidil is safe for men with hair loss, with no significant changes in heart rate or blood pressure.
5 citations
,
April 2022 in “Pharmaceutics” Minoxidil nanoparticles significantly boost hair growth in mice compared to regular minoxidil.
9 citations
,
October 2020 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil is an effective and well-tolerated treatment for hair growth in alopecia patients.
October 2024 in “Clinical and Experimental Dermatology” The combination treatment didn't work better than minoxidil alone and caused more menstrual issues.
November 2024 in “International Society of Hair Restoration Surgery” Systemic minoxidil is generally safe for older adults, but caution is needed for those with heart risks.
April 2016 in “Journal of Investigative Dermatology”