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research A Neutralizing Prolactin Receptor Antibody Whose In Vivo Application Mimics the Phenotype of Female Prolactin Receptor-Deficient Mice

14 citations , August 2015 in “Endocrinology”

The antibody 005-C04 blocks prolactin receptors, causing reversible infertility, impaired lactation, and hair regrowth in female mice.

research Impact of Combined Baricitinib and FTI Treatment on Adipogenesis in Hutchinson–Gilford Progeria Syndrome and Other Lipodystrophic Laminopathies

4 citations , May 2023 in “Cells”

Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.

research Autosomal dominant monilethrix with incomplete penetrance due to a novel KRT86 mutation in a Chinese family

April 2024 in “Anais Brasileiros de Dermatologia”

research Reverse Protein Engineering Of Firefly Luciferase

January 2014

The protein's size was reduced, but more work is needed to confirm its function.

research TMPRSS2: A Key Host Factor in SARS-CoV-2 Infection and Potential Therapeutic Target

4 citations , June 2025 in “Medeniyet Medical Journal”

TMPRSS2 is crucial for COVID-19 infection and is a potential target for treatment.

research Development of a new therapeutic approach based on peptide nanoparticles delivering CRISPR-Cas9 for the specific targeting of KRAS mutations

September 2023 in “HAL (Le Centre pour la Communication Scientifique Directe)”

Peptide nanoparticles can effectively deliver CRISPR-Cas9 to target KRAS mutations in cancer.

research Gene Expression and Localization of LAMTOR3 in the Skin Cells of Liaoning Cashmere Goats

4 citations , March 2018 in “Animal biotechnology”

The LAMTOR3 gene is involved in cashmere goat hair growth and is affected by certain treatments and other genes.

research MicroRNAs in skin tissue engineering

39 citations , May 2015 in “Advanced drug delivery reviews”

MicroRNAs could improve skin tissue engineering by regulating cells and changing the skin's bioactive environment.

Variable Expressivity of Syndromic BMP4-Related Eye, Brain, and Digital Anomalies: A Review of the Literature and Description of Three New Cases

research Variable expressivity of syndromic BMP4-related eye, brain, and digital anomalies: A review of the literature and description of three new cases

7 citations , May 2019 in “European Journal of Human Genetics”

BMP4-related anomalies can cause a wide range of eye, brain, and hand/foot problems, and new cases show this variability.

research Autosomal recessive monilethrix: Novel variants of the DSG4 gene in three Chinese families

5 citations , February 2022 in “Molecular genetics & genomic medicine”

New gene variants linked to a rare inherited hair loss disorder were found in three Chinese families.

research MEX3A regulates Lgr5 ⁺ stem cell maintenance in the developing intestinal epithelium

27 citations , February 2020 in “EMBO Reports”

MEX3A is crucial for maintaining intestinal stem cells in mice.

research Abstract C4: Sp2: A regulator of stem cell differentiation and tumorigenesis

December 2009 in “Cancer Research”

Over-expression of Sp2 can lead to cancer by preventing proper stem cell differentiation.

research 307 Phenotypic-genotypic expansion of plectinopathy in a patient with muscular dystrophy and immune-mediated myasthenia gravis

November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

A patient with a new PLEC gene mutation showed symptoms of both muscular dystrophy and myasthenia gravis, which improved with steroid treatment.

Complete Defect in PA-PLA1α Secretion Function Leading to Autosomal Recessive Woolly Hair and Hypotrichosis: Insights from a Novel Compound Heterozygous LIPH Variant Study in a Chinese Pedigree

research Complete defect in PA-PLA1α secretion function leading to autosomal recessive woolly hair and hypotrichosis: insights from a novel compound heterozygous LIPH variant study in a Chinese pedigree

May 2025 in “Frontiers in Genetics”

A new genetic variant in the LIPH gene causes hair growth issues in a Chinese patient.

research Upregulation of interfollicular epidermal and hair infundibulum β-catenin expression in Gsdma3 mutant mice

11 citations , June 2012 in “Acta histochemica”

Mice with a Gsdma3 gene mutation have thicker skin and longer hair follicle openings due to increased β-catenin levels.

research Regulation of Tmem30b-mediated apical membrane homeostasis in auditory outer hair cells is critical for hearing

April 2026 in “Proceedings of the National Academy of Sciences”

The study identifies Tmem30b as a crucial regulator in outer hair cells (OHCs) for hearing, highlighting its role in maintaining the structure of hair bundles in the cochlea. Tmem30b, a phospholipid-flippase chaperone, initially localizes to the nuclear membrane and later stabilizes in the stereocilia and cuticular plate. Tmem30b −/− mice show early-onset hearing loss due to disorganized OHC stereocilia, starting at P7. Tmem30b partners with Atp8b1 to regulate phospholipid asymmetry, and disruption of this complex destabilizes OHC bundles. AAV-mediated delivery of Tmem30b to hair cells corrects stereocilia defects in Tmem30b −/− and Atp8b1 −/− mice, and overexpression of Tmem30b protects against noise-induced and aminoglycoside-induced hearing loss. The findings suggest Tmem30b–Atp8b1–mediated lipid regulation as a potential therapeutic target for hearing loss.

research Regulation of Mitochondrial Oxidative Metabolism by Tumor Suppressor FLCN

81 citations , November 2012 in “Journal of the National Cancer Institute”

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

research 14. 膠原病患者における心理状態の統計学的観察(第45回日本心身医学会東北地方会演題抄録)

August 1999 in “心身医学”

Suppressing ODC activity reduces tumor growth in hair follicles.

research Localized in vivo genotypic and phenotypic correction of the albino mutation in skin by RNA-DNA oligonucleotide

130 citations , January 2000 in “Nature biotechnology”

research Isolation and Characterization of a Putative Keratin-Associated Protein Gene Expressed in Embryonic Skin of Mice

22 citations , July 1998 in “Journal of Investigative Dermatology”

The 4C32 gene may help in mouse skin development and differentiation.

Exosome-Derived Long Non-Coding RNA AC010789.1 Modified by FTO and hnRNPA2B1 Accelerates Growth of Hair Follicle Stem Cells Against Androgen Alopecia by Activating S100A8/Wnt/β-Catenin Signaling

research Exosome‐derived long non‐coding RNA AC010789.1 modified by FTO and hnRNPA2B1 accelerates growth of hair follicle stem cells against androgen alopecia by activating S100A8/Wnt/β‐catenin signalling

January 2025 in “Clinical and Translational Medicine”

A specific RNA can help hair growth in baldness by boosting stem cell activity.

research Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1

380 citations , March 2000 in “Proceedings of the National Academy of Sciences”

Overexpressing GLI-1 in mice skin can cause tumors like human basal cell carcinomas.

research Novel Missense Mutation in the P-Box of Androgen Receptor in a Patient with Androgen Insensitivity Syndrome

3 citations , January 2008 in “Endocrine journal”

A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

research H3K4me3 regulates the transcription of RSPO3 in dermal papilla cells to influence hair follicle morphogenesis and development

1 citations , August 2025 in “Epigenetics & Chromatin”

H3K4me3 helps control RSPO3 to influence hair growth and development.

research Analyse de la régulation du gène Hairless et identification des voies de signalisation affectées chez les mutants «bald Mill Hill».

January 2008 in “HAL (Le Centre pour la Communication Scientifique Directe)”

The mutant HR bmh protein affects hair follicle formation by failing to repress vitamin D receptor activity.

research Specific inhibition of FGF5-induced cell proliferation by RNA aptamers

15 citations , February 2021 in “Scientific Reports”

RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.

research 328 The transcription factor CEBPB is a novel hub gene and multi-functional disease driver in Psoriatic skin inflammation

November 2022 in “Journal of Investigative Dermatology”

ILC1-like cells can cause alopecia areata by themselves.

CENPV Is a Novel CYLD-Interacting Molecule Regulating Ciliary Acetylated Tubulin

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