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BI 2536 had limited effectiveness against several advanced cancers and caused significant side effects.

A new model helps predict treatment success in girls with early puberty.

Finasteride use is linked to a lower risk of bladder cancer, especially in Caucasians and Hispanics.

Researchers developed a reliable method to measure testosterone and epitestosterone in urine for medical and anti-doping use.

EVG staining helps tell apart follicular scars from follicular streamers, aiding in diagnosing different types of hair loss.

Multiple eye conditions were studied, highlighting the importance of various imaging methods for diagnosis, the vision side effects of drugs tamoxifen and Propecia, and the usefulness of optical coherence tomography for diagnosing and monitoring macular and retinal diseases.

The study found that polymorphous light eruption varies among patients and can be distinguished from benign summer light eruption by the time it takes for symptoms to appear after sun exposure.

Moles on the scalp are more common in people with more body moles and atypical moles, but not linked to balding.

Centralized imaging provides more accurate and consistent hair loss measurements in alopecia areata.

Skin and mucous symptoms are key for diagnosing autoimmune connective tissue diseases.

Mice with CBS deficiency are healthier on a low-methionine diet.

The lentiviral array can monitor and predict gene activity during stem cell differentiation.

The Pemphigus Disease Area Index and Autoimmune Bullous Skin Disorder Intensity Score are the best tools for assessing pemphigus severity.

DNA virus-induced tumors have consistent isozyme profiles, unlike other tumor types.

Intralesional cidofovir may be a viable alternative treatment for SCC.

The method effectively detects MeT and TP in dried blood spots after cream application.

The method effectively identifies and measures seven banned substances in cosmetics.

The model improves understanding of androgen interactions by focusing on signal intensity and system capacity.

Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.

AMH is a promising biomarker for diagnosing PCOS.

Sonidegib is effective and safe for treating advanced basal cell carcinoma, but biopsies are needed to confirm tumor clearance.

A comprehensive scoring system for alopecia areata severity is needed.

Ear creases might indicate heart disease risk, needing more research.

Certain gene variations and different levels of BDNF and CRH hormones are linked to vitiligo.

MK-0773 is a moderate inhibitor of the SRD5A2 enzyme.

Tissue-specific variation in mutant load complicates genetic counseling and prenatal diagnosis.

Mefloquine, an antimalarial drug, is effective in killing melanoma cells resistant to other treatments by causing lethal stress in the cells.

The new AI software predicts melanoma outcomes more accurately than traditional methods.

Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.