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Three molecular subtypes of advanced skin T-cell lymphoma were identified, with potential biomarkers for predicting treatment response and disease progression.

HR protein causes abnormal hair cycles by increasing Tgf-β2 and reducing miR-31.

mTORC2 is crucial for healthy skin barrier by regulating lipids and filaggrin.

Topical tacrolimus reduces certain growth factors in hair follicles.

Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.

TGFα gene mutation in mice causes abnormal skin, wavy hair, curly whiskers, and sometimes eye inflammation.

Patients with mycosis fungoides have a higher risk of heart disease.

A new mutation in the KRT86 gene causes a hair disorder with variable expression.

The model helps test drugs for clubfoot fibrosis by mimicking cell environments and shows minoxidil reduces harmful collagen links.

Folliculotropic mycosis fungoides has a worse prognosis than other types, with survival rates varying significantly based on subtype and organ involvement.

Recognizing minor skin lesions can help identify serious cancer syndromes.

The research developed new fortilin protein constructs for potential heart disease treatments.

Decreasing MIG6 can increase the movement and invasiveness of MEK-inhibited mutant NRAS melanoma, particularly when stimulated by EGF.

miR-140-y helps control feather growth in geese by affecting the Wnt signaling pathway.

Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.

Lack of TG2 increases fat storage and lowers cell cleanup in skin oil cells.

Researchers found genes and microRNAs that control curly fleece in Chinese Tan sheep.

Intermediate filaments are crucial for cell structure and function, regulated by specific genes and proteins.

TG5 helps maintain hair follicle health, while TG3 aids in hair shaft development.

Mycophenolate mofetil is a good alternative for autoimmune hepatitis patients who can't tolerate azathioprine.

Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

Tofacitinib was more effective than methotrexate for treating alopecia areata.

Dynlt3 is important for melanosome transport and skin coloration.

Mycophenolate mofetil improved skin condition in a man with nephrogenic fibrosing dermopathy.

Tet1/2/3 enzymes affect hair follicle cell development by influencing BMP signaling.

A gene mutation in mice causes skin defects and early death.

Tofacitinib improved ulcerative colitis, skin ulcers, and hair loss in a patient who didn't respond well to other treatments.

Endothelin-1 helps amelanotic melanocytes stick and move better on certain proteins.

A20 protein is crucial for normal skin and hair development.

Activating TLR5 in the gut can extend lifespan and improve health in aged mice.