209 citations
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September 2008 in “Dermatologic Therapy” Androgens can both increase and decrease hair growth in different parts of the body.
150 citations
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August 1992 in “Genes & Development” TNF alpha in skin cells causes weight loss, hair and fat issues, and skin inflammation in mice.
124 citations
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February 2018 in “Nature Reviews Genetics” Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.
64 citations
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July 2011 in “Dermatologic Therapy” Scalp cooling can prevent chemotherapy-induced hair loss, and certain treatments can speed up hair regrowth, but more research is needed for better treatments.
51 citations
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October 2002 in “British Journal of Dermatology” Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.
47 citations
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July 2013 in “Pharmacological Reviews” Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
27 citations
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January 2012 in “Current Topics in Microbiology and Immunology” Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
25 citations
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April 1949 in “The journal of experimental zoology” Testosterone applied to rabbit skin increases skin cell growth and changes skin structure.
22 citations
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March 2012 in “Molecular Medicine Reports” DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.
16 citations
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December 2011 in “Actas Dermo-Sifiliográficas” Propranolol is effective and safe for treating infantile hemangioma, but more research is needed for dosing and monitoring guidelines.
14 citations
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April 2005 in “Experimental Dermatology” Stressed fibroblasts greatly increase melanin production in hair, skin, and eye cells, mainly due to a growth factor called bFGF.
10 citations
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January 1985 in “Elsevier eBooks” Active oxygen species might be involved in skin tumor growth, but their exact role is unclear.
7 citations
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April 2012 in “Clinical investigation” Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.
3 citations
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June 2017 in “Methods” Researchers created a model to understand heart aging, highlighting the role of microRNAs and identifying key genes and pathways involved.
January 2015 in “Our Dermatology Online” Intralesional triamcinolone is the most effective treatment for hair regrowth in alopecia areata patients.
January 2015 in “Przegla̧d dermatologiczny” Intralesional triamcinolone is the most effective treatment for alopecia areata, followed by excimer light therapy, and then topical minoxidil. The scalp responds better to treatment than the beard area.
January 2007 in “Elsevier eBooks” Alopecia areata is a reversible, autoimmune-related hair loss that can have significant emotional impact and uncertain treatment effectiveness.
January 2001 in “Cambridge University Press eBooks” Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.
October 2020 in “Journal of Pakistan Association of Dermatology” Platelet-rich plasma therapy is more effective than minoxidil lotion for increasing hair count in men with hair loss, with mild side effects and high satisfaction.
11 citations
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May 2015 in “Stem Cells Translational Medicine” Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.
4 citations
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June 1998 in “The Journal of Clinical Endocrinology & Metabolism” KGF and its receptor are found in enlarged prostate tissue and KGF strongly increases cell growth.
46 citations
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May 2020 in “Cureus” Zinc is vital for immune health, growth, and preventing diarrhea.
1066 citations
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March 2010 in “Nature Reviews Molecular Cell Biology” MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.
471 citations
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October 2012 in “Cellular and Molecular Life Sciences” Understanding developmental pathways can improve wound healing treatments.
438 citations
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October 2010 in “Oncogene” Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.
253 citations
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April 2014 in “Drugs” Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.
222 citations
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January 2005 in “Endocrine journal” Melatonin is important for skin health and protection, and can be made by the skin or applied to it.
218 citations
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April 2008 in “Genes & Development” Skin stem cells help repair damage and maintain healthy skin.
211 citations
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May 2018 in “Trends in cell biology” Different types of skin cells play specific roles in development, healing, and cancer.
159 citations
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July 2006 in “Endocrine Reviews” Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.