January 2023 in “Research Square (Research Square)” Blacks and Hispanics have higher chances of alopecia areata than Whites.
January 2020 in “Research Portal Denmark” A short male anogenital distance may indicate incomplete masculinization due to disrupted androgen action.
January 2020 in “Archives of urology” Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.
October 2015 in “Elsevier eBooks” Finasteride helps hair growth and prostate issues but may cause sexual side effects and increase tumor risk.
759 citations
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February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
556 citations
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September 2008 in “Genes & Development” Wnt signaling is vital for cell growth, development, and cancer research.
403 citations
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December 2018 in “Cell stem cell” Understanding phenotypic plasticity is crucial for developing effective cancer therapies.
278 citations
,
March 2013 in “Gut” Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.
249 citations
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November 2003 in “Clinical endocrinology” Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.
153 citations
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March 2017 in “Endocrine” Male pattern baldness involves genetics, hormones, and needs better treatments.
148 citations
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December 2018 in “Journal of autoimmunity” Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
119 citations
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June 2005 in “Journal of Molecular and Cellular Cardiology” Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.
118 citations
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May 2015 in “European journal of pharmaceutics and biopharmaceutics” The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.
72 citations
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April 2008 in “The Journal of urology/The journal of urology” Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.
70 citations
,
August 2020 in “Nanomaterials” Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.
68 citations
,
September 2018 in “International Journal of Molecular Sciences” Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.
63 citations
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March 2011 in “Clinical Endocrinology” Evaluate postmenopausal women with high androgen levels using medical history, physical exams, lab tests, and imaging to manage health risks.
58 citations
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January 2018 in “International Journal of Women's Dermatology” Alopecia significantly lowers women's quality of life, with psychological and social challenges, highlighting the importance of early treatment and support.
56 citations
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February 2010 in “PLOS ONE” Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.
47 citations
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March 2018 in “Journal of Pharmaceutical and Biomedical Analysis” Researchers identified new compounds in Platycladi Cacumen and found variations in its flavonoid content, which could aid in its quality control.
44 citations
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April 2006 in “Expert opinion on drug safety” Gefitinib can cause skin problems, diarrhea, and nausea, but rarely causes severe lung disease or hair loss.
42 citations
,
March 2008 in “Molecular and Cellular Endocrinology” Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.
39 citations
,
June 2019 in “Toxins” Bee venom might be a good alternative treatment for various skin conditions because it has many healing properties.
38 citations
,
November 2013 in “Journal of The American Academy of Dermatology” Higher BMI links to worse hair loss in Taiwanese men.
38 citations
,
December 2011 in “Anais Brasileiros de Dermatologia” Skin diseases significantly lower the quality of life for patients in southern Brazil, especially for younger, single, and lower-income individuals.
36 citations
,
June 2001 in “Neuroscience Letters” Finasteride may affect fetal brain development and increase arousal, but more research is needed for safety confirmation.
33 citations
,
December 2005 in “Archives of dermatology” Alefacept showed some effectiveness for alopecia areata but needs more research.
25 citations
,
July 2014 in “Hong Kong medical journal” Some skin disorders might be linked to H. pylori infection, but more research is needed to confirm this.
25 citations
,
December 2001 in “Expert Opinion on Pharmacotherapy” Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.
23 citations
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August 2018 in “Anais Brasileiros De Dermatologia” Both androgenetic alopecia and alopecia areata negatively impact quality of life, with no significant difference between them.