359 citations
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January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
356 citations
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March 2012 in “Trends in Plant Science” Auxin and ethylene hormones both work together and against each other to control plant growth.
354 citations
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February 2011 in “Genes & Development” EZH1 and EZH2 are crucial for healthy hair growth and skin repair.
351 citations
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February 2010 in “Nature Cell Biology” Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.
343 citations
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October 2015 in “Endocrine Practice” The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.
309 citations
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May 1993 in “Journal of The American Academy of Dermatology” Horizontal scalp biopsy sections effectively diagnose and predict MPAA, with follicular density and inflammation impacting hair regrowth.
304 citations
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July 2006 in “Journal of The American Academy of Dermatology” Videodermoscopy improves diagnosis of hair and scalp disorders and may reduce scalp biopsies.
299 citations
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January 2018 in “Journal of Clinical Investigation” Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
295 citations
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June 2009 in “Science” Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.
286 citations
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April 2009 in “The journal of neuroscience/The Journal of neuroscience” TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.
269 citations
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May 2002 in “Journal of Neuroscience” Stress increases neurosteroids that help prevent seizures.
254 citations
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September 2014 in “Menopause” The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.
223 citations
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October 2020 in “Microsystems & Nanoengineering” Microtechnology methods improve organoid production for medical research.
220 citations
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March 2020 in “Advanced functional materials” Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.
218 citations
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April 2012 in “British Journal of Dermatology” Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.
216 citations
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October 1997 in “American Journal of Ophthalmology” Using the eye pressure medication latanoprost can cause excessive hair growth and darker eyelashes on the treated eye.
209 citations
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March 1989 in “Journal of The American Academy of Dermatology” Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.
198 citations
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July 2011 in “Cochrane library” Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.
193 citations
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August 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Hair loss common in Australia; men affected earlier, more often than Asians; women less concerned.
192 citations
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September 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.
188 citations
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March 2018 in “Frontiers in Immunology” Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.
187 citations
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April 2019 in “npj Regenerative Medicine” Wharton's jelly secretomes are best for promoting blood vessel growth.
187 citations
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January 1994 in “The New England Journal of Medicine” Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.
184 citations
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December 2018 in “Nature Communications” Researchers created human hair follicles using a new method that could help treat hair loss.
178 citations
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May 2006 in “Developmental Dynamics” Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.
168 citations
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August 2000 in “American Journal of Pathology” Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.
168 citations
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December 1986 in “Cancer Chemotherapy and Pharmacology” Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.
165 citations
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January 2008 in “Journal of biomaterials science. Polymer ed.” The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.
162 citations
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August 2002 in “Survey of Ophthalmology” Latanoprost can make eyelashes longer, thicker, and darker.
160 citations
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December 2016 in “Journal of biophotonics” Low-level laser therapy, now called photobiomodulation, is recognized for its broad medical applications and scientific backing.