9 citations
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July 2011 in “The Journal of Sexual Medicine” Hair loss drugs like finasteride may cause lasting sexual and mood side effects, and more research is needed to understand these risks.
99 citations
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October 2006 in “BMC clinical pharmacology” Finasteride may cause slight depression and anxiety.
August 2023 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Minoxidil users may experience hair discoloration, especially with long-term use and a family history of gray hair.
11 citations
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June 2013 in “Journal of Chemical Education” Minoxidil detects nitrite in water, creating a simple, cheap test.
April 2024 in “Journal of cosmetic dermatology” Minoxidil is less effective on eyebrows and eyelashes than scalp hair because these areas have lower enzyme activity needed to activate the drug.
26 citations
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December 2023 in “Prostate International” Medications for BPH can have significant side effects, so understanding these risks is important for treatment decisions.
8 citations
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November 2011 in “Journal of Medical Case Reports” Bupropion may help treat trichotillomania when fluoxetine doesn't work.
18 citations
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October 2022 in “JCI Insight” Abnormal amino acid metabolism may worsen rosacea symptoms.
1 citations
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July 2024 in “The International Journal of Medical Science and Health Research” 5α-reductase inhibitors may help with prostate cancer but could increase the risk of severe tumors, so careful use is advised.
1 citations
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February 2022 in “JAMA Dermatology” Minoxidil and finasteride are FDA-approved treatments for male hair loss, but off-label use of oral minoxidil, dutasteride, and higher doses of finasteride and minoxidil is increasing.
August 2025 in “Archives of Dermatological Research” Oral minoxidil may help with pediatric hair disorders but has notable side effects.
June 2025 in “Revista Foco” JAK inhibitors effectively treat severe alopecia areata with manageable side effects.
January 2026 in “Revista Colombiana de Ciencias Químico Farmacéuticas” Combining Minoxidil and finasteride is more effective for hair growth but may cause side effects.
February 2023 in “Reactions Weekly”
14 citations
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September 2003 in “Archives of Dermatology” Finasteride may not stop severe hair loss after stopping minoxidil.
May 2025 in “BMJ Case Reports” Minoxidil can cause temporary vision loss and color blindness.
2 citations
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November 2009 in “Korean journal of chemical engineering” Adding Brij 78 to minoxidil microparticles in a certain solution helps them stick to the skin better and prevents clumping.
48 citations
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February 2006 in “Molecular and Cellular Endocrinology” 5α-reductase inhibitors may reduce male fertility and could be used for male contraception.
8 citations
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July 2019 in “Pure and Applied Chemistry” Some natural compounds from Iris plants can block enzymes related to certain disorders, with a few affecting both targeted enzymes.
14 citations
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December 1998 in “The Journal of Clinical Endocrinology and Metabolism” MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.
September 2022 in “Reactions Weekly” April 2015 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” December 2014 in “대한피부미용학회지” Natural hair-loss preventers from plants and herbs are becoming popular due to fewer side effects and added benefits.
2 citations
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July 1982 in “British Journal of Dermatology” Retinol acetate can reduce the harmful effects of the drug benoxaprofen on white blood cells.
1 citations
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November 2024 in “Expert Opinion on Drug Safety” Aromatase inhibitors can cause various adverse reactions, so monitoring is crucial.
April 2015 in “한국생물공학회 학술대회” Finasteride reduces melanin production in skin cells.
5 citations
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November 2020 in “JAMA Dermatology” Finasteride may cause side effects; more research needed.
6 citations
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February 2020 in “Journal of Natural Products” A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.
April 2010 in “Nature Reviews Urology”
13 citations
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December 2012 in “Canadian Urological Association Journal” 5ARIs like finasteride can help prevent prostate cancer and treat BPH, but guidelines should be updated to reflect this.