120 citations
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February 2009 in “Apoptosis” Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
111 citations
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January 2007 in “Seminars in cell & developmental biology” Hair, teeth, and mammary glands develop similarly at first but use different genes later.
77 citations
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July 2012 in “Journal of Investigative Dermatology” Wnt10b overexpression can regenerate hair follicles, possibly helping treat hair loss and alopecia.
71 citations
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June 2001 in “American Journal of Pathology” The p53 protein helps control hair follicle shrinking by promoting cell death in mice.
68 citations
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December 1991 in “Annals of the New York Academy of Sciences” Hair growth can be induced by certain cells found at the base of hair follicles, and these cells may also influence hair development and regeneration.
55 citations
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April 2018 in “Advanced Healthcare Materials” Hydrogels could lead to better treatments for wound healing without scars.
48 citations
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December 2004 in “Differentiation” Tooth papilla cells can help regenerate hair follicles and grow hair.
45 citations
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September 2012 in “Life Sciences” Aconiti Ciliare Tuber extract may help hair grow by activating a specific cell signaling pathway.
42 citations
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October 2011 in “Seminars in Cell & Developmental Biology” Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
39 citations
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March 2009 in “Archives of Dermatological Research” Apigenin may help promote hair growth and could treat hair loss.
35 citations
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February 2019 in “Cell Communication and Signaling” BMP6 and Wnt10b control whether hair follicles are resting or growing.
34 citations
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December 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” Rat vibrissa follicles are useful for studying hair growth cycles, especially the transition from pro-anagen to anagen.
33 citations
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February 2016 in “Journal of Experimental Botany” ROOT HAIR SPECIFIC 10 (RHS10) reduces the length of root hairs in Arabidopsis plants.
30 citations
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December 2018 in “Trends in Endocrinology and Metabolism” Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.
30 citations
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February 2017 in “Histochemistry and Cell Biology” TPA promotes hair growth by increasing stem cell activity and activating specific cell signals.
29 citations
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April 2020 in “Biomolecules” The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.
28 citations
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August 2018 in “BMC genomics” DNA methylation changes are linked to hair growth cycles in goats.
28 citations
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December 2008 in “Laboratory investigation” Activin activation in skin cells speeds up wound healing without affecting scar quality.
28 citations
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July 2008 in “Developmental Biology” Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.
25 citations
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May 2014 in “Facial Plastic Surgery” PRFM may help treat hair loss, especially in mild cases.
22 citations
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May 2021 in “Nature Communications” Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.
22 citations
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December 2013 in “Molecular biology of the cell” ILK is essential for proper hair follicle development and structure.
20 citations
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February 2017 in “International Journal of Dermatology” Platelet-based therapies using a patient's own blood show promise for skin and hair regeneration but require more research for confirmation.
20 citations
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January 2013 in “Cell & Bioscience” Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.
19 citations
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November 2018 in “Nutrients” Annurca apple extract may protect mouse hair from damage by chemotherapy and could help treat hair loss without promoting cancer growth.
18 citations
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August 2015 in “Biochemical and Biophysical Research Communications” XEDAR triggers a specific signaling pathway in cells.
17 citations
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June 2012 in “Journal of experimental zoology. Part B, Molecular and developmental evolution” Hair in mammals likely evolved from glandular structures, not scales.
16 citations
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January 2005 in “The International Journal of Developmental Biology” Hex gene plays a crucial role in starting feather development in chick embryos.
14 citations
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July 2019 in “Experimental and Molecular Medicine” Nanog gene boosts stem cells, helps hair growth, and may treat hair loss.
14 citations
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September 2018 in “Asian-Australasian Journal of Animal Sciences” Rex rabbits' hair follicles develop dynamically in the first 8 weeks, with key genes and proteins changing over time.