2 citations
,
August 2023 in “Development” Hair follicles in the back of the rosette fancy mouse have reversed orientations due to a gene mutation.
218 citations
,
October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.
April 2021 in “Journal of Investigative Dermatology” A deep learning model was developed to help diagnose trichothiodystrophy by analyzing hair patterns.
6 citations
,
January 1997 in “Medical Mycology” The fungus Piedraia hortae damages hair by slowly breaking down its layers, leading to long-lasting infection.
1 citations
,
June 2016 in “Medicina” Monilethrix is a genetic disorder causing brittle hair, diagnosed using tricoscopy.
11 citations
,
December 2014 in “The American journal of pathology” A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.
4 citations
,
September 2020 in “Journal of Cutaneous Pathology”
6 citations
,
August 2012 in “The Journal of Pediatrics” A 12-year-old girl was diagnosed with monilethrix, a genetic condition causing fragile, beaded hair that breaks easily, with no effective treatment available.
January 2006 in “Dianzi xianwei xuebao” Netherton syndrome causes specific skin and hair changes that help in early diagnosis.
March 2026 in “Journal of genetics and genomics/Journal of Genetics and Genomics” February 1999 in “The anatomical record” Two mouse mutants have defective hair cuticle cross-linking.
October 2017 in “Chinese Journal of Dermatology” 11 citations
,
November 2019 in “The FASEB Journal” A mutation in the MAP2 gene causes reduced hair follicle density, leading to hairlessness.
47 citations
,
September 2008 in “British Journal of Dermatology” Ludwig pattern hair loss in women results from varying sensitivity in hair follicles, causing fewer visible hairs.
1 citations
,
January 2014 in “Indian Journal of Dermatology, Venereology and Leprology” The 'Swiss cheese' pattern in scalp biopsies can indicate trichotillomania, not just alopecia areata.
August 2020 in “Textile research journal” The model helps understand how wool fiber structure affects its strength and flexibility.
3 citations
,
January 2004 in “Journal of Wildlife Diseases” A deer fawn in South Dakota was the first cervid found with congenital hypotrichosis, a condition causing sparse or missing hair.
1 citations
,
January 2024 in “Animal Research and One Health” Mouse models are essential for studying and improving genetic traits in agriculture.
27 citations
,
November 2015 in “American Journal of Primatology” Stable isotope analysis of hair helps study primate diets over time non-invasively.
1 citations
,
February 2018 in “Australasian journal of dermatology” Advanced imaging techniques are crucial for accurately diagnosing Monilethrix, a rare hair disorder.
2 citations
,
July 2025 in “Journal of the European Academy of Dermatology and Venereology” The girl in "The Girl with a Pearl Earring" might have had alopecia areata, causing her lack of eyebrows and sparse eyelashes.
7 citations
,
April 2000 in “Mammalian Genome” A new mutation in mice causes crooked whiskers and messy hair.
6 citations
,
August 2001 in “PubMed” The stump-tailed macaque is a good model for studying human hair loss, but it's expensive and hard to find, while rodent models are promising for understanding hair growth and finding new treatments.
9 citations
,
February 2016 in “Cambridge University Press eBooks” The conclusion is that self-concept, shame, and emotion regulation are key factors in hoarding disorder, body dysmorphic disorder, and trichotillomania, and should be targeted in treatment and research.
February 2018 in “Medical Hypotheses” Male pattern hair loss may have evolved to promote younger fathers for offspring health and survival, encouraging monogamy and paternal nurturing.
91 citations
,
December 2006 in “Proceedings of the National Academy of Sciences” Hair patterns in mice are controlled by both a global system dependent on Fz6 and a local self-organizing system.
July 2023 in “Veterinary pathology” White-tailed deer can get a hair loss condition that might make them more vulnerable to environmental threats.
53 citations
,
October 2014 in “Free radical biology & medicine” Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.
A white-tailed deer fawn in South Dakota was the first cervid found with congenital hypotrichosis, a condition causing sparse or missing hair.
1 citations
,
November 2025 in “Science Advances” Two gene variants cause white spots in cattle.