September 2025 in “Cell Reports” Skin stretching can improve vaccine delivery through hair follicles and boost immune response.
July 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Thrombin-preconditioned exosomes speed up wound healing and reduce scarring.
January 2025 in “Journal of Controlled Release” A new microneedle patch helps treat hair loss by improving drug delivery to hair follicles.
January 2025 in “ACS Applied Materials & Interfaces” Nanoparticles with specific drugs can help regrow hair in alopecia areata.
CRH causes hair loss by reducing cell survival in hair follicles.
April 2023 in “Journal of Investigative Dermatology” Mutations in the SHH pathway in certain skin cells can cause skin tumors and abnormal hair growth.
January 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Newly born mesenchymal cells quickly spread out in response to tissue tension during early development.
Hedgehog signaling can create new hair follicles in adult skin but may increase cancer risk.
Hedgehog signaling can create new hair follicles but may also cause tumors.
April 2016 in “Journal of Investigative Dermatology” Removing alkaline phosphatase from human skin cells hinders the creation of new hair follicles.
December 2009 in “Cancer Research” Over-expression of Sp2 can lead to cancer by preventing proper stem cell differentiation.
September 2004 in “Experimental Dermatology” The model effectively studies how sensory nerves interact with skin components, aiding research on wound healing and hair growth.
5 citations
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April 2024 in “Biology” Improving human hair follicle models is crucial for better hair loss treatments.
October 2025 in “Biomedicines” Terminalia chebula fruit extract helps hair growth by reducing DHT and boosting hair cell activity.
May 2014 in “Journal of Investigative Dermatology” Scientists developed tools to observe hair regeneration in real time and assess skin health, using glowing mice and light-controlled genes.
7 citations
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July 2008 in “Experimental Dermatology” The study concluded that a protein important for hair strength is regulated by certain molecular processes and is affected by growth phases.
Some fibroblast growth factors may promote hair growth similarly to minoxidil and could potentially treat hair loss.
138 citations
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June 2012 in “Genes & Development” Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
108 citations
,
July 2004 in “American Journal of Pathology” Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.
101 citations
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January 1997 in “Journal of Investigative Dermatology Symposium Proceedings” Nerves and chemicals in the body can affect hair growth and loss.
96 citations
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June 2017 in “Nature Communications” A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.
25 citations
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September 2018 in “Molecular Biology of the Cell” Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.
23 citations
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May 2013 in “Virology” HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.
August 2025 in “Regenerative Therapy” Exosomes from platelet-rich plasma can help regrow hair by reducing oxidative stress.
March 2023 in “Biomedicine & Pharmacotherapy” GPR40 agonists help hair growth through the protein ANGPTL4.
291 citations
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April 2010 in “Gastroenterology” Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.
133 citations
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January 2009 in “Nature” Lgr5 and the vitamin D receptor are key in controlling skin inflammation and tumor risk in mice.
42 citations
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May 2016 in “Annual Review of Cell and Developmental Biology” Fat cells are important for tissue repair and stem cell support in various body parts.
12 citations
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August 2022 in “Journal of Controlled Release” A new microneedle patch effectively promotes hair growth by increasing blood vessel formation around hair follicles.
6 citations
,
June 2022 in “Frontiers in Bioengineering and Biotechnology” The gel with icariin speeds up wound healing, reduces scarring, and helps hair growth by controlling BMP4 signaling. It also reduces inflammation and improves wound quality in mice, adapts to different wound shapes, and gradually releases icariin to aid healing. It also prevents too much collagen and myofibroblast formation during skin healing.