4 citations
,
March 2017 in “Development” Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
3 citations
,
January 2018 in “PeerJ” Researchers created a long-lasting mouse skin cell strain that may help with hair growth research and treatments.
September 2023 in “Nature Communications” Immune cells are essential for skin regeneration using biomaterial scaffolds.
2 citations
,
January 1998 in “Dermatology” Stopping forehead irritation and using hydrocortisone helped a man's skin, Martinique has lower melanoma rates, a man had an allergy to a specific antifungal, another had unexplained cysts, certain drugs can cause skin reactions without always being interrelated, a link between Fanconi anemia and a skin condition was suggested, high levels of a certain protein may play a role in a type of psoriasis, and there's a need to study the connection between scalp pain and hair loss.
46 citations
,
August 2012 in “Experimental Dermatology” Engineered skin can grow chimeric hair follicles only with mouse dermal papilla cells.
45 citations
,
July 2009 in “Journal of Investigative Dermatology” The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.
34 citations
,
April 2018 in “EMBO journal” The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.
28 citations
,
August 2015 in “Journal of Drug Targeting” The new CoQ10 gel protects mouse skin better against aging from UV light than the old gel.
6 citations
,
February 2013 in “Journal of Visualized Experiments” The method quickly analyzes hair growth genes and shows that blocking Smo in skin cells stops hair growth.
28 citations
,
March 2010 in “Histochemistry and Cell Biology” Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.
April 2017 in “Journal of Investigative Dermatology” Hair loss patterns differ between males and females due to 5 master regulators and JAK-STAT signaling affects hair growth.
66 citations
,
August 2001 in “Experimental Dermatology” Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.
16 citations
,
September 2016 in “Experimental Dermatology” Two-photon microscopy effectively tracks live stem cell activity in mouse skin with minimal harm and clear images.
155 citations
,
May 2016 in “Nature communications” Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.
18 citations
,
February 2006 in “Genomics” A new genetic mutation in mice causes permanent hair loss and skin wrinkling.
14 citations
,
January 2014 in “Cells Tissues Organs” Ionizing radiation causes irreversible skin damage, with single doses leading to acute injury and hair graying, and fractional doses causing more severe long-term tissue damage.
3 citations
,
August 2022 in “International Journal of Molecular Sciences” TSC2-/meth cells can cause skin lesions, hair growth, and lung issues, and may be treated with chromatin remodeling agents.
110 citations
,
July 2017 in “Immunology” Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.
62 citations
,
November 2009 in “Aging Cell” Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.
53 citations
,
October 2012 in “The FASEB Journal” Bimatoprost, a glaucoma medication, may also help treat hair loss.
46 citations
,
May 2012 in “Molecular and Cellular Endocrinology” Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.
13 citations
,
May 2022 in “Cell discovery” The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.
157 citations
,
December 2015 in “Journal of the American Academy of Dermatology” A man with vitiligo and alopecia saw quick skin and hair improvement with ruxolitinib, but skin color gains were lost after stopping treatment.
59 citations
,
September 2008 in “Experimental dermatology” Both mouse and rat models are effective for testing alopecia areata treatments.
43 citations
,
July 2014 in “Experimental Dermatology” Hair follicles can help wounds heal faster and this knowledge could be used to treat chronic skin ulcers, with a potential use of a special stem cell hydrogel to enhance healing.
June 2010 in “Melanoma research” LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.
5 citations
,
March 2016 in “Experimental and molecular pathology” Mice with alopecia areata had wider lymphatic vessels in their skin.
74 citations
,
June 2018 in “Cell death and disease” Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.
35 citations
,
May 2021 in “Nature communications” The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.
16 citations
,
March 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.