62 citations
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December 1966 in “Endocrinology” Injecting α-MSH made mice's hair turn black.
17 citations
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April 2023 in “ACS Biomaterials Science & Engineering” Silk fibroin microneedles can effectively treat vitiligo by promoting skin pigmentation.
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April 1998 in “Journal of Investigative Dermatology” ACTH promotes hair growth in mink, but α-MSH does not.
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September 2018 in “International Journal of Cosmetic Science” Palmitoyl tetrapeptide-20 may help reduce hair greying and increase melanin production.
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January 2025 in “Regenerative Biomaterials” Exosomes from Pinctada martensii mucus can safely reduce melanin production, offering a new treatment for skin pigment issues.
January 2026 in “Aging and Disease” The α-MSH-MC1R-cAMP pathway does not protect skin cells from UVA damage.
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January 1995 in “PubMed” Mouse melanocyte structure and function are influenced by genetics, hormones, and environmental factors.
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April 1965 in “General and Comparative Endocrinology” The pituitary gland controls seasonal fur color changes in weasels.
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June 1992 in “International Journal of Dermatology” Pregnancy often causes skin changes like darkening, stretch marks, and hair growth, which may improve after childbirth.
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May 1986 in “Clinics in endocrinology and metabolism” Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.
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July 1988 in “Journal of The American Academy of Dermatology” Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.
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January 1981 in “Springer eBooks” Environmental factors like temperature and nutrition affect hair growth, with humans showing seasonal hair growth differences.
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December 1981 in “Journal of Endocrinology” α-MSH increases melanin production in moulting hair follicles, while AVT inhibits it.
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December 2006 Tribulus terrestris extract significantly increases MSH expression and melanin production in mouse hair follicles.
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May 2017 in “Journal of the European Academy of Dermatology and Venereology” The study found no significant difference in stress hormone levels between people with alopecia areata and healthy individuals, suggesting that the disease is not caused by an overactive stress response system.
February 2025 in “Endocrine Reviews” Hormones affect skin aging, but only topical retinoids and estrogens are used in treatments now.
The PI's development is closely linked to skin and hair pigmentation in macaques.
March 2005 in “Journal of the American Academy of Dermatology” Recognizing minor skin lesions can help identify serious cancer syndromes.
489 citations
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June 2005 in “The FASEB Journal” Human hair follicles can produce cortisol like the body's stress response system.
139 citations
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October 2005 in “Journal of Investigative Dermatology” The nail matrix has a reduced immune response, protecting it from autoimmunity.
135 citations
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March 2000 in “Journal of Biological Chemistry” Agouti and AGRP affect pigmentation and obesity, with implications for metabolic disorders.
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October 1999 in “Annals of the New York Academy of Sciences” The Skin POMC System affects hair growth and skin responses to stress.
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August 2005 in “Endocrinology” αMSH may help regulate immune responses in hair follicles and its disruption could lead to hair loss.
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July 1981 in “Journal of Endocrinology” α-MSH and cyclic AMP boost melanin production, while cyclic GMP and melatonin reduce it.
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July 2000 in “Journal of Histochemistry & Cytochemistry” POMC-derived peptides are important for skin functions like immune response and stress management.
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November 1997 in “Journal of Neural Transmission” Seborrhea in Parkinson's disease may be linked to hormones, not autonomic impairment.
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August 2005 in “Dermatologic Clinics” Stress and emotional factors can worsen skin conditions by affecting the immune system.
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October 2004 in “Experimental Dermatology” α-MSH may help treat skin inflammation and fibrosis.
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November 2014 in “Experimental Dermatology” Injecting alpha-melanocyte-stimulating hormone in mice improved skin healing and reduced scarring.
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May 1992 in “International Journal of Dermatology” Some alternative vitiligo treatments show promise, but none are as effective as psoralens and UVA.