January 1997 in “Elsevier eBooks” Hair and nails are skin parts that develop early and serve protective and functional roles.
May 1991 in “Current problems in dermatology” Skin issues can indicate immune system problems.
March 1987 in “Journal of The American Academy of Dermatology” Oral spironolactone and isotretinoin are effective for treating acne.
January 1982 in “Side effects of drugs annual” High doses of certain vitamins can cause serious side effects and health risks.
306 citations
,
April 2019 in “International Journal of Molecular Sciences” The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
172 citations
,
May 2018 in “Nature” Mammalian organs regenerate using stem cells and cell plasticity, but this ability declines with age.
165 citations
,
January 2008 in “Journal of biomaterials science. Polymer ed.” The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.
139 citations
,
December 2020 in “Cell Stem Cell” Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
139 citations
,
August 2018 in “Development” The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.
104 citations
,
May 2003 in “Endocrinology” Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.
97 citations
,
March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
65 citations
,
June 2021 in “Frontiers in Pharmacology” Targeting abnormal lung fluid metabolism could reduce COVID-19 deaths and ventilator use.
62 citations
,
July 1993 in “Journal of Investigative Dermatology” Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.
54 citations
,
September 2013 in “Fertility and Sterility” Finasteride can reduce fertility in some men, but stopping it increases sperm count.
48 citations
,
July 2008 in “Acta Biochimica et Biophysica Sinica” Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.
41 citations
,
October 2024 in “Nature Communications” A new wearable LED device helps heal chronic infected wounds at home.
36 citations
,
January 2018 in “Burns & Trauma” NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.
30 citations
,
December 2018 in “Trends in Endocrinology and Metabolism” Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.
28 citations
,
January 2017 in “Critical Reviews in Therapeutic Drug Carrier Systems” Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.
26 citations
,
May 2021 in “International Journal of Molecular Sciences” Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.
26 citations
,
January 2014 in “Cell Structure and Function” Human sweat glands contain stem cells capable of self-renewal and forming different cell types.
26 citations
,
February 2009 in “Drug Development Research” 17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.
24 citations
,
June 2018 in “Reviews in endocrine and metabolic disorders” Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.
24 citations
,
May 2018 in “Journal of Molecular Endocrinology” The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.
23 citations
,
January 2007 in “Archives of Andrology” Finasteride may negatively affect male fertility.
17 citations
,
January 2023 in “Nanoscale Advances” The microneedle arrays effectively promote wound healing and have potential for clinical use.
17 citations
,
June 2012 in “Journal of experimental zoology. Part B, Molecular and developmental evolution” Hair in mammals likely evolved from glandular structures, not scales.
16 citations
,
August 2014 in “Archives of Pharmacal Research” Special nanoparticles increased skin absorption of hair loss treatments with fewer side effects.
16 citations
,
January 2005 in “The International Journal of Developmental Biology” Hex gene plays a crucial role in starting feather development in chick embryos.
13 citations
,
November 2005 in “Veterinary Dermatology” A dog's skin calcification condition resolved without treatment after a bacterial infection.