research Unmet Medical Needs in Chronic, Non-communicable Inflammatory Skin Diseases
There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
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research COVID-19: Understanding Inter-Individual Variability and Implications for Precision Medicine
The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.
research What should it take to describe a substance or product as 'sperm-safe'
Products should be called 'sperm-safe' only after thorough, well-designed tests.
research Hair and scalp disorders in ethnic populations
Different hair care practices and conditions affect African American hair and scalp health, requiring specialized knowledge for treatment.
research Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome
Some drugs may reduce prostatitis symptoms short-term with few side effects.
research Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update
The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
research High proliferation and delamination during skin epidermal stratification
High proliferation and cell delamination drive early skin development, while later stages may not rely on cell division orientation.
research Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle
Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
research Efficacy of tofacitinib in treatment of alopecia universalis in two patients
Tofacitinib was effective in treating hair loss in two patients with alopecia universalis.
research Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: position paper and recommendations of the ESC Working Group on Cellular Biology of the Heart
The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.
research Androgens modify Wnt agonists/antagonists expression balance in dermal papilla cells preventing hair follicle stem cell differentiation in androgenetic alopecia
Androgens prevent hair growth by changing Wnt signals in cells.
research The biology of hair diversity
Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.
research Skin diseases associated with atopic dermatitis
People with atopic dermatitis are more likely to develop other skin conditions due to shared genetics and immune pathways.
research Acne in the adult female patient: a practical approach
Hormonal therapies are safe and effective for treating adult women's acne.
research Drug Repurposing - Hypothesis, Molecular Aspects and Therapeutic Applications
Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
research Guidelines for the diagnosis and treatment of male-pattern and female-pattern hair loss, 2017 version
Use finasteride, dutasteride, and minoxidil for hair loss treatment.
research Madarosis: A marker of many Maladies
Losing eyelashes or eyebrows can be a sign of many different health problems and needs a careful approach to treat effectively.
research Treatment options for alopecia: an update, looking to the future
The document concludes that there are various treatments for different types of alopecia, but more research is needed for evidence-based treatments.
research Estimation of biological heart age using cardiovascular magnetic resonance radiomics
Obesity and lifestyle strongly affect heart aging.
research What does acne genetics teach us about disease pathogenesis?
Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.
research Smad4-dependent desmoglein-4 expression contributes to hair follicle integrity
Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.
research Cell Cycle Regulation and Regeneration
Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
research Current Perspectives on the Physiological Activities of Fermented Soybean-Derived Cheonggukjang
Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.
research Exploring pericyte and cardiac stem cell secretome unveils new tactics for drug discovery
New drugs for heart disease may be developed from molecules secreted by stem cells.
research Integrated safety analysis of baricitinib in adults with severe alopecia areata from two randomized clinical trials
Baricitinib for severe alopecia areata is generally safe, with common side effects like infections and acne, and low rates of serious complications.
research Guidelines for the Use of Acitretin in Psoriasis
Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.
research Emerging concepts about prenatal genesis, aberrant metabolism and treatment paradigms in polycystic ovary syndrome
PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.
research An update of the pathogenesis of frontal fibrosing alopecia: What does the current evidence tell us?
The current understanding of frontal fibrosing alopecia involves immune, genetic, hormonal factors, and possibly environmental triggers, but more research is needed for effective treatments.
research Strengthening the Skin with Topical Delivery of Keratinocyte Growth Factor-1 Using a Novel DNA Plasmid
Applying a special DNA plasmid to the skin can make it thicker and stronger.
research Conventional and novel stem cell based therapies for androgenic alopecia
Stem cell technologies and regenerative medicine, including platelet-rich plasma, show promise for hair restoration in treating hair loss, but more research is needed.