9 citations
,
October 2024 in “Burns & Trauma” Air-liquid interface culture improves hair follicle development in skin organoids.
Hair bulb cells can create skin-like tissues for potential skin repair.
January 2006 in “Journal of Sun Yat-sen University” Engineered skin using stem cells and collagen sponge effectively healed and regenerated complex skin features in mice.
June 2020 in “Journal of Investigative Dermatology” Scientists successfully grew mini hair follicles using human skin cells, which could help treat baldness.
6 citations
,
June 2024 in “Biofabrication” A small 3D skin model helps study how immune cells move in the skin.
58 citations
,
November 2012 in “PLoS ONE” Human skin cells can be turned into versatile stem cells, but their ability to do so decreases with repeated use.
A skin model using hair and skin cells can mimic human skin for research.
17 citations
,
September 2016 in “Stem cells translational medicine” Using bioreactors, scientists can grow more skin stem cells that keep their ability to regenerate skin and hair.
46 citations
,
October 2023 in “Science Advances” 3D bioprinting can now create skin with hair-like structures for medical use.
129 citations
,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
10 citations
,
August 2023 in “Developmental cell” The research maps the complex development of early mouse skin, identifying diverse cell types and their roles in forming skin layers and structures.
18 citations
,
January 1994 in “Skin Pharmacology and Physiology” Human dermal fibroblasts and hair papilla cells help outer root sheath cells grow and develop properly.
17 citations
,
January 1997 in “Cell and Tissue Research” Scientists developed a method to grow human fetal skin and digits in a lab for 3-4 weeks, which could help study skin features and understand genetic interactions in tissue formation.
15 citations
,
March 2020 in “Experimental and Therapeutic Medicine” The skin is a large organ that plays a role in the immune system.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The article concludes that creating a detailed map of normal human skin at the single-cell level is important.
2 citations
,
April 2019 in “Experimental Dermatology” The article concludes that studying how skin forms is key to understanding skin diseases and improving regenerative medicine.
9 citations
,
June 2021 in “Biological reviews/Biological reviews of the Cambridge Philosophical Society” Understanding molecular pathways is key to improving organ regeneration.
2 citations
,
January 1989 Researchers developed a method to grow skin-like tissue from hair cells.
March 2007 in “Journal of Plastic Reconstructive & Aesthetic Surgery” A new method was developed to create better skin models for healing and reconstruction.
31 citations
,
May 2019 in “Nature communications” Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.
22 citations
,
April 1987 in “International Journal of Dermatology” Skin organ culture helps us understand skin biology and diseases better.
December 2024 in “Medical Review” Organoids help study and treat genetic diseases, offering personalized medicine and therapy testing.
8 citations
,
March 2025 in “Developmental Biology” Integumentary organs adapt and evolve for survival, with potential uses in regenerative medicine.
A comprehensive human skin cell atlas was created to better understand skin biology and disease.
4 citations
,
June 2007 in “PubMed” Engineered skin with specific cells can effectively repair skin and restore its function.
January 2011 in “Hispania Judaica bulletin” Mechanical forces are crucial for hair regeneration in skin organoids.
33 citations
,
September 2016 in “British journal of dermatology/British journal of dermatology, Supplement” Human hair follicle dermal cells can effectively replace other cells in engineered skin.
211 citations
,
May 2018 in “Trends in cell biology” Different types of skin cells play specific roles in development, healing, and cancer.
40 citations
,
January 2016 in “Elsevier eBooks” The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
January 2008 in “Yearbook of Dermatology and Dermatologic Surgery” One type of progenitor cell can maintain normal skin in mice.