research PKC downregulation upon rapamycin treatment attenuates mitochondrial disease
Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
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research Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–like Autoimmune Disease
AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
research Exploring pericyte and cardiac stem cell secretome unveils new tactics for drug discovery
New drugs for heart disease may be developed from molecules secreted by stem cells.
research Characterization and quantification of wound-induced hair follicle neogenesis using in vivo confocal scanning laser microscopy
In vivo confocal scanning laser microscopy is an effective, non-invasive way to study and measure new hair growth after skin injury in mice.
research Neuropsychiatric Systemic Lupus Erythematosus Presenting as Bipolar I Disorder With Catatonic Features
A girl initially thought to have a psychiatric disorder was later found to have a lupus-related condition, which improved with proper treatment.
research Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development
Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.
research LncRNA PlncRNA‑1 regulates proliferation and differentiation of hair follicle stem cells through TGF‑β1‑mediated Wnt/β‑catenin signal pathway
PlncRNA-1 helps hair follicle stem cells grow and develop by controlling a specific cell signaling pathway.
research The diagnosis of nonclassic congenital adrenal hyperplasia due to 21-hydroxylase deficiency, based on serum basal or post-ACTH stimulation 17-hydroxyprogesterone, can lead to false-positive diagnosis
Using 17-hydroxyprogesterone levels to diagnose nonclassic congenital adrenal hyperplasia can result in many incorrect diagnoses.
research Stem cells and aberrant signaling of molecular systems in skin aging
Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
research Investigation of six novel susceptibility loci for male androgenetic alopecia in women with female pattern hair loss
Six new hair loss factors in men not linked to female hair loss.
research Biallelic HEPHL1 variants impair ferroxidase activity and cause an abnormal hair phenotype
Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.
research Bilateral Half-Head Comparison of 1% Anthralin Ointment in Children with Alopecia Areata
1% anthralin ointment is effective and safe for treating severe alopecia areata in children.
research Current Understanding of the Pathways Involved in Adult Stem and Progenitor Cell Migration for Tissue Homeostasis and Repair
The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.
research Local structure of human hair spatially resolved by sub-micron X-ray beam
Human hair has a new region with ordered filaments and the cuticle contains β-keratin sheets.
research The Genetics of Human Skin Disease
Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
research Human gene correlation analysis (HGCA): A tool for the identification of transcriptionally co-expressed genes
The HGCA tool helps identify genes that work together by analyzing their co-expression patterns.
research Does the Recipient Site Influence the Hair Growth Characteristics in Hair Transplantation?
The place where hair is transplanted can affect its growth and survival rates.
research Pre-clinical non-viral vectors exploited forin vivoCRISPR/Cas9 gene editing: an overview
Non-viral vectors show promise for safe and effective CRISPR/Cas9 gene editing in treating diseases.
research Predicting hair cortisol levels with hair pigmentation genes: a possible hair pigmentation bias
Darker hair may lead to higher cortisol readings, suggesting a need to adjust for hair color in studies.
research The reduction of selenium(IV) by boreal Pseudomonas sp. strain T5-6-I – Effects on selenium(IV) uptake in Brassica oleracea
Pseudomonas sp. T5-6-I bacteria increase selenium uptake in Brassica oleracea plants by 130%.
research The Metabolism and Control Mechanism of Human Hair Follicles
Human hair follicles have a unique metabolism that changes between growth stages and may contribute to baldness.
research Retinoid Metabolism Is Altered in Human and Mouse Cicatricial Alopecia
Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.
research Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations
Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
research Yellow and orange in cutaneous lesions: clinical and dermoscopic data
Yellow and orange colors are important for diagnosing certain skin conditions.
research Investigation of four novel male androgenetic alopecia susceptibility loci: no association with female pattern hair loss
No link found between new male baldness genes and female hair loss.
research Relationship of Early-Onset Baldness to Prostate Cancer in African-American Men
Early-onset baldness is linked to a higher risk of aggressive prostate cancer in African-American men, especially before age 60.
research Efficient Intradermal Delivery of Superoxide Dismutase Using a Combination of Liposomes and Iontophoresis for Protection against UV-Induced Skin Damage
Liposomes and iontophoresis effectively deliver protective enzymes into the skin against UV damage.
research Microimaging of hairless rat skin by magnetic resonance at 900 MHz
MRI can effectively image skin structures noninvasively.
research Cutaneous wound healing: canine allogeneic ASC therapy
Using stem cells from fat tissue can significantly improve wound healing in dogs.
research Expanding the Clinical and Mutational Spectrum of Recessive AEBP1-Related Classical-Like Ehlers-Danlos Syndrome
The study concludes that mutations in the AEBP1 gene can cause a form of Ehlers-Danlos syndrome and should be considered in diagnosis.